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Biocatalysis of linoleic acid to conjugated linoleic acid
Lipids, 2006AbstractCLA refers to a group of geometrical and positional isomers of linoleic acid (LA) with conjugated double bonds. CLA has been reported to have diverse health benefits and biological properties. Traditional organic synthesis is highly capital‐intensive and results in an isomeric mixture of CLA isomers.
Sibel, Irmak +4 more
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Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids
Organic Letters, 2019The syntheses of linoleic acid esters of hydroxy linoleic acids (LAHLAs) present in oat oil and human serum have been achieved, providing access to material for testing and the determination of the stereochemistry of the natural compounds. While 9- and 13-LAHLAs were found to be a mixture of enantiomers 15-LAHLA is generated in a single optical form in
Huijing Wang +7 more
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Conjugated linoleic acid production from linoleic acid by lactic acid bacteria
Journal of the American Oil Chemists' Society, 2002AbstractAfter screening 14 genera of lactic acid bacteria, Lactobacillus plantarum AKU 1009a was selected as a potential strain for CLA production from linoleic acid. Washed cells of L. plantarum with high levels of CLA production were obtained by cultivation in a nutrient medium with 0.06% (wt/vol) linoleic acid (cis‐9,cis‐12‐octadecadienoic acid ...
Shigenobu Kishino +4 more
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Conjugated linoleic acid metabolism
Current Opinion in Lipidology, 2002Conjugated linoleic acid (CLA) is a naturally occurring fatty acid that is produced by a bio-hydrogenation process in the rumen, and thus is present in dairy products and ruminant meat. In this case the predominant isomer formed is 9cis,11trans. However, CLA includes 28 positional and geometrical isomers, of which only 9cis,11trans and 10trans,12cis ...
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Nature, 1945
IN connexion with work on the purification of soybean lipoxidase1, an investigation was undertaken to identify the primary products formed from linoleic acid when it was oxidized by molecular oxygen with this enzyme or with inorganic catalysts.
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IN connexion with work on the purification of soybean lipoxidase1, an investigation was undertaken to identify the primary products formed from linoleic acid when it was oxidized by molecular oxygen with this enzyme or with inorganic catalysts.
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Abstract Linoleic acid (LA), an essential n-6 polyunsaturated fatty acid, exerts wide-ranging physiological functions as both a structural lipid and a bioactive precursor. Incorporated into phospholipids, LA maintains membrane fluidity, lipid raft composition, and transmembrane signaling.
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Tumour fatty acid metabolism in the context of therapy resistance and obesity
Nature Reviews Cancer, 2021Andrew J Hoy +2 more
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