Results 51 to 60 of about 15,472 (258)

Distribution of conjugated linoleic acid and metabolites in different lipid fractions in the rat liver

Journal of Lipid Research, 2001
Conjugated linoleic acid (CLA) is known to provide certain health benefits in experimental animal models. The major CLA isomer in food is c 9,t11-CLA.
Sebastiano Banni, Gianfranca Carta, Elisabetta Angioni, Elisabettta Murru, Paolo Scanu, Maria Paola Melis, Dale E. Bauman, Susan M. Fischer, Clement Ip   +8 more
doaj   +1 more source

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

Archaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares, Eriola Jakoel, Ron Be’eri, Oded Lipschits, Ronny Neumann, Yuval Gadot   +5 more
wiley   +1 more source

Role of the protozoan Isotricha prostoma, liquid-, and solid-associated bacteria in rumen biohydrogenation of linoleic acid

Animal, 2009
From the simultaneous accumulation of hydrogenation intermediates and the disappearance of Isotricha prostoma after algae supplementation, we suggested a role of this ciliate and/or its associated bacteria in rumen biohydrogenation of unsaturated fatty ...
C. Boeckaert, D.P. Morgavi, J.-P. Jouany, L. Maignien, N. Boon, V. Fievez   +5 more
doaj   +1 more source

Mechanistic investigation of Liujing Toutong tablet in the treatment of cerebral ischemia–reperfusion injury in rats by the integration of serum pharmacochemistry and metabolomics

Animal Models and Experimental Medicine, EarlyView.
The research strategy for pharmacodynamics, serum pharmacochemistry, metabolomics, and network pharmacology analysis method in intervention effects of LTT are illustrated. Abstract Background Liujing Toutong tablet (LTT) is a traditional Chinese patent medicine.
Zihan Yu, Ke Pei, Xiulin Wang, Wenling Li, Hongchang Li, Wangyang Xie, Xianglong Meng, Tingting Zhao, Yan Ning, Haixin Liu, Wenbin He   +10 more
wiley   +1 more source

In vitro study of dietary factors affecting the biohydrogenation shift from trans-11 to trans-10 fatty acids in the rumen of dairy cows

Animal, 2012
On the basis of the isomer-specific effects of trans fatty acids (FA) on human health, and the detrimental effect of t10,c12-conjugated linoleic acid (CLA) on cows’ milk fat production, there is a need to identify factors that affect the shift from trans-
A. Zened, F. Enjalbert, M.C. Nicot, A. Troegeler-Meynadier   +3 more
doaj   +1 more source

Effects of conjugated linoleic acid on linoleic and linolenic acid metabolism in man [PDF]

British Journal of Nutrition, 2006
Evidence from animal studies suggests that conjugated linoleic acid (CLA) modulates plasma and tissue appearance of newly synthesized PUFA. The effects of a 1·2g (0·5% energy) daily intake of thecis-9,trans-11 (c9,t11) isomer of CLA,trans-10,cis-12 (t10,c12) isomer of CLA or olive oil (placebo) on linoleic acid (LA) and linolenic acid (LNA) metabolism ...
Anu M, Turpeinen, Sonja, Bärlund, Riitta, Freese, Peter, Lawrence, J Thomas, Brenna   +4 more
openaire   +2 more sources

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Influence of diet enriched with conjugated linoleic acids on their distribution in tissues of rats with DMBA induced tumors

Lipids in Health and Disease, 2010
Backround Conjugated linoleic acids (CLA) are a group of positional and geometric isomers of linoleic acid with proven beneficial influence on health. They show e.g. anticarcinogenic, antiobesity, and antiatherogenic effect. Milk, dairy products and meat
Kazimierska Weronika, Dudek Agnieszka, Tokarz Andrzej, Białek Agnieszka, Bielecki Wojciech   +4 more
doaj   +1 more source

Nitrogen fertilization of Cayman Blend grass (Urochloa hybrid cv. GP0423 + GP4467) on the chemical composition and fatty acid profile in milk from grazing cows

Revista Científica
Conjugated linoleic acid (CLA) is a constituent of bovine milk that has been shown to possess protective effects against various diseases, including cancer. Therefore, there is a compelling rationale for increasing the content of CLA in milk.
Isabel Cristina Acosta–Balcazar, Yuridia Bautista–Martínez, Benigno Estrada–Drouaillet, José Felipe Orzuna–Orzuna, Miguel Ruíz–Albarran, Jorge David Guiot–García, Lorenzo Danilo Granados–Rivera   +6 more
doaj   +1 more source