Results 211 to 220 of about 86,643 (308)

Optimization of novel compounds using computer‐aided drug design for treatment of cardiac arrhythmia

British Journal of Pharmacology, EarlyView.
Background and Purpose Loss‐of‐function mutations of the voltage‐gated Kv7.1 (KCNQ/KCNE1) channels lead to cardiac arrhythmia such as long QT syndrome, characterized by a prolonged QT interval . One strategy to correct the prolonged QT interval is to design molecules that activate KCNQ1/KCNE1 channels and restore the QT interval.
Jessica Jowais, Laura M. Castro‐Gonzalez, Alessia Golluscio, D. Peter Tieleman, H. Peter Larsson   +4 more
wiley   +1 more source

Acute plant-derived C18 fatty acid exposure was associated with changes in muscle 5-LOX protein abundance and volatile profiles in triploid rainbow trout (<i>Oncorhynchus mykiss</i>). [PDF]

Food Chem (Oxf)
Si Y, Song Y, Huang D, Chen Y, Sun J, Wu Z, Ma R, Sun G, Meng Y.   +8 more
europepmc   +1 more source

Stability of potato glycoalkaloids under heating conditions - Reactions with fatty acids. [PDF]

Curr Res Food Sci
Mittau K, Meyers C, Rawel HM, Smit I, Schmidt M, Rohn S.   +5 more
europepmc   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Genetic associations between polyunsaturated fatty acids and alopecia areata. [PDF]

Medicine (Baltimore)
Liu Q, Cai Y, Li W, Shi W, Yu L, Cai X.
europepmc   +1 more source

Comparative Study of Laboratory Diets for Piophila casei: Beneficial Effects of Infant Formula Supplementation

Entomologia Experimentalis et Applicata, EarlyView.
The infant formula‐based diet (F), the whole powder milk diet (P), and dry‐cured ham (H) were evaluated for rearing Piophila casei. H accelerated development, promoted earlier reproduction, and achieved the highest demographic performance but showed practical limitations linked to substrate deterioration. F enhanced larval survival and adult longevity,
Diletta Missere, Maria Luisa Dindo, Antonio Martini, Alberto Lanzoni   +3 more
wiley   +1 more source

The effects of conjugated linoleic acids on breast cancer: A systematic review.

Adv Biomed Res, 2016
Arab A, Akbarian SA, Ghiyasvand R, Miraghajani M.   +3 more
europepmc   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Roles of Metabolomics in Allergic Rhinitis: From Cell to Bedside Investigations. [PDF]

Int J Mol Sci
Saligupta P, Lao-Araya M, Chattipakorn SC, Chattipakorn N, Thonusin C.   +4 more
europepmc   +1 more source

Fecal Lipid Metabolites and Microbiota Alterations in Dogs With Concurrent Atopic Dermatitis and Adverse Food Reaction

Allergy, EarlyView.
Akane Hayashi, Sayaka Kakiyama, Koji Kawano, Naomi Harima‐Mizusawa, Toshihide Kobayashi, Chiaki Kaga, Koji Kobayashi, Takahisa Murata   +7 more
wiley   +1 more source