Results 21 to 30 of about 3,253 (256)
Case Reports in Psychiatry, 2022 Background/Objective. Thyrotoxicosis, a condition resulting from excessive peripheral thyroid hormone, is typically accompanied by thyroid function tests demonstrating a high free thyroxine (free T4) with appropriate suppression of thyroid-stimulating ...
Benjamin A. Pallant +2 more
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Frontiers in Endocrinology, 2021 BackgroundThe standard treatment of hypothyroidism is levothyroxine (LT-4). However, there are several controversies regarding treatment of hypothyroid patients.AimTo investigate the Swedish endocrinologists’ use of thyroid hormones in hypothyroid and ...
Tereza Planck +8 more
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Design of the Optimal Trial of Combination Therapy
Frontiers in Endocrinology, 2020 Patients who take levothyroxine monotherapy to treat hypothyroidism frequently experience residual symptoms despite TSH testing at target levels. Trials have been conducted to evaluate the potential benefit of combination therapy with levothyroxine and ...
Anne R. Cappola
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Endokrynologia Polska, 2021 INTRODUCTION: Over the past several years new evidence on the management of hypothyroidism has emerged, which has influenced recommendations from professional bodies.
Tomasz Bednarczuk +7 more
doaj +1 more source
Cell Communication and Signaling, 2020 Background Inhibitors targeting immune checkpoint were proved effective in cancer immunotherapy, such as PD-1/PD-L1 blockade. The novel immune checkpoint TIGIT/PVR plays critical roles in suppressing the anti-tumor effects of CD8+ T and NK cells, and ...
Xiuman Zhou +12 more
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The effect of liothyronine supplementation on electroconvulsive therapy-induced cognitive impairment in patients with mood disorders: a clinical trial [PDF]
International Archives of Health SciencesObjectives: This study aimed to assess the effects of Liothyronine supplementation on memory performance in patients diagnosed with mood disorders (major depressive or bipolar disorder).Methods: This double-blind controlled clinical trial was conducted ...
Pooya Hazegh +3 more
doaj +1 more source
Frontiers in Immunology, 2022 Myxedema coma is a critical disorder with high mortality rates. Disruption of the compensatory mechanism for severe and long-term hypothyroidism by various causes leads to critical conditions, including hypothermia, respiratory failure, circulatory ...
Hiroshi Ito +15 more
doaj +1 more source
Scope and limitations of iodothyronine deiodinases in hypothyroidism. [PDF]
, 2015 The coordinated expression and activity of the iodothyronine deiodinases regulate thyroid hormone levels in hypothyroidism. Once heralded as the pathway underpinning adequate thyroid-hormone replacement therapy with levothyroxine, the role of these ...
Bianco, Antonio C. +3 more
core +1 more source
Combination Therapy for Hypothyroidism: Rationale, Therapeutic Goals, and Design
Frontiers in Endocrinology, 2020 Hypothyroidism is a common condition with a wide spectrum of etiologies and clinical manifestations. While the majority of patients affected by hypothyroidism respond well to levothyroxine, some patients do not and complain of symptoms despite adequate ...
Ritu Madan, Francesco S. Celi
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Thyroxine treatment with softgel capsule formulation. Usefulness in hypothyroid patients without malabsorption [PDF]
, 2018 Background: Levothyroxine sodium (LT4) is the therapy of choice for hypothyroidism. In the last decade, new LT4 formulations, such as liquid and softgel capsules, became available. Even if some evidence has been reached in the efficacy of liquid LT4 in
Centanni, Marco +3 more
core +2 more sources