Results 31 to 40 of about 3,253 (256)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease [PDF]

, 2017
This research was funded by the Scottish Universities Life Science Alliance (SULSA) assay development fund. This research was also kindly supported by The Rosetrees Trust and The Alzheimer’s Society, specifically The Barcopel Foundation, and partly ...
Andrew Pannifer, Angus Morrison, Frank J. Gunn-Moore, Gemma Baillie, Hughes M., Laura Aitken, Philip S. Jones, Stuart P. McElroy, Terry K. Smith   +8 more
core   +2 more sources

Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]

, 2012
In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P, Fountoulakis KN, Hans-Jürgen Möller, Kirsch I, Kirsch I, Kirsch I, Konarski JZ, Konstantinos N Fountoulakis, Moncrieff J   +8 more
core   +1 more source

Hypothyroidism: The difficulty in attributing symptoms to their underlying cause

Frontiers in Endocrinology, 2023
Common symptoms of overt hypothyroidism are non-specific and include fatigue, lethargy, and dry skin. Although the diagnosis is considered to be straightforward, no single symptom can be used to identify patients with overt hypothyroidism, while many ...
Heleen I. Jansen, Heleen I. Jansen, Heleen I. Jansen, Anita Boelen, Anita Boelen, Anita Boelen, Annemieke C. Heijboer, Annemieke C. Heijboer, Annemieke C. Heijboer, Annemieke C. Heijboer, Eveline Bruinstroop, Eveline Bruinstroop, Eric Fliers, Eric Fliers   +13 more
doaj   +1 more source

The Management of Thyroid Abnormalities in Chronic Heart Failure. [PDF]

, 2019
KEY POINTS Normal triiodothyronine (T3) levels are essential to preserve cardiac morphology and function. Overt and subclinical hypothyroidism are associated with an increased risk of heart failure, and levothyroxine is able to improve ...
Biondi, B
core   +1 more source

Effect of Liothyronine Treatment on Quality of Life in Female Hypothyroid Patients With Residual Symptoms on Levothyroxine Therapy: A Randomized Crossover Study

Frontiers in Endocrinology, 2022
ObjectiveThe effects of levothyroxine (LT4)/liothyronine (LT3) combination therapy on quality of life (QoL) in hypothyroid patients former on LT4 monotherapy have been disappointing.
Betty Ann Bjerkreim, Betty Ann Bjerkreim, Sara Salehi Hammerstad, Sara Salehi Hammerstad, Hanne Løvdal Gulseth, Tore Julsrud Berg, Tore Julsrud Berg, Lars Johan Omdal, Sindre Lee-Ødegård, Erik Fink Eriksen, Erik Fink Eriksen   +10 more
doaj   +1 more source

Polypharmacy among anabolic-androgenic steroid users: A descriptive metasynthesis [PDF]

, 2015
Background: As far as we are aware, no previous systematic review and synthesis of the qualitative/descriptive literature on polypharmacy in anabolic-androgenic steroid(s) (AAS) users has been published. Method: We systematically reviewed and synthesized
AJ Gruber, AJ Gruber, AJ Gruber, AJ McBride, AJ Viera, Astrid Bjørnebekk, B Hegazy, B Larance, C Ahlgrim, C Wilson-Fearon, Cecilie Schou Andreassen, CN Schäfer, CS Cornford, D Hoff, D Moher, D Moher, D Sagoe, D Sagoe, DA Malone Jr, DL Katz, Dominic Sagoe, E Chahla, E Pappa, F Klötz, G Kanayama, G Kanayama, G Kanayama, G McKillop, GS Goldfield, H Angoorani, H Geyer, HB Moss, HB Moss, HG Pope Jr, HG Pope Jr, IBM Corp, J Bilard, JA Smith, JD Wines, Jim McVeigh, JR Hoffman, K Skårberg, K Skårberg, K Skårberg, KA Clauson, L Degenhardt, L Lundholm, LJ Silvester, M Chandler, M Dunn, M Evans-Brown, Marie-Stella Essilfie, MJ Evans-Brown, N Gårevik, P Korkia, P Korkia, P Lenehan, PJ Fudala, PJ Perry, PJ Perry, R Davies, R Peters, R Shaw, RH Strauss, RP Kusserow, RT Dawson, S Darke, SM Filiault, Ståle Pallesen, T Dodge, T Hildebrandt, TA Pagonis, V Tallon, VD Hope, W Rashid   +74 more
core   +2 more sources

Type 3 Deiodinase and Consumptive Hypothyroidism: A Common Mechanism for a Rare Disease [PDF]

, 2013
The major product secreted by the thyroid is thyroxine (T4), whereas most of the biologically active triiodothyronine (T3) derives from the peripheral conversion of T4 into T3. The deiodinase enzymes are involved in activation and inactivation of thyroid
Cristina Luongo, Domenico Salvatore, Fausta Alfano, Luigi Trivisano   +3 more
core   +2 more sources

Unemployment and initiation of psychotropic medication:a case-crossover study of 2,348,552 Norwegian employees [PDF]

, 2016
Objectives: The study investigated initiation of psychotropic medication in relation to unemployment in the months before, during and after job loss to detect the period of greatest risk.Methods: The Norwegian working population in 2004 (N=2 348 552) was
Bjorngaard, Johan Hakon, Gunnell, David, Kaspersen, Silje, Ose, Solveig, Pape, Kristine   +4 more
core   +2 more sources

Subclinical thyroid dysfunction and cardiovascular diseases: 2016 update. [PDF]

, 2017
Subclinical thyroid dysfunction comprises subclinical hypothyroidism (SHypo), defined as elevated thyroid-stimulating hormone (TSH) by normal free thyroxine (FT4), and subclinical hyperthyroidism (SHyper) with decreased or undetectable TSH and normal FT4.
Collet, T.H., Floriani, C., Gencer, B., Rodondi, N.   +3 more
core   +3 more sources