Results 151 to 160 of about 178,847 (317)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Produção enzimática de biodiesel em modo contínuo em meio pressurizado [PDF]

, 2009
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de AlimentosEste trabalho investiga a produção em modo contínuo de ésteres etílicos de ácidos graxos de óleo de soja em fluidos ...
Dalla Rosa, Clarissa
core  

Screening of lipase inhibitors from Scutellaria baicalensis extract using lipase immobilized on magnetic nanoparticles and study on the inhibitory mechanism

, 2016
Scutellaria baicalensis is a traditional Chinese medicinal plant possessing a wide variety of biological activities. In this work, lipase immobilized on magnetic nanoparticles (LMNPs) was used as solid phase extract absorbent for screening of lipase ...
Wan, LH, Liang, J, Hu, JJ, Jiang, XL, Liao, X, Liao, X (reprint author), Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China., Liu, YM (reprint author), Jackson State Univ, Dept Chem & Biochem, 1400 Lynch St, Jackson, MS 39217 USA., Liu, YM   +7 more
core   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara, Dilip Kumar Singh, Sandhya Subash, Guihua Yue, Deepak Ahire, Chris Bohl, Maciej Czerwinski, Stephanie Helmstetter, Scott Heyward, Robert S. Jones, Cyrus Khojasteh, Ryota Kikuchi, Priyanka Kulkarni, Bin Ma, Bernard Murray, Chris Seib, Bill Smith, David M. Stresser, Mitchell E. Taub, Ting Wang, Bhagwat Prasad   +20 more
wiley   +1 more source

Lipase-Catalyzed Polycondensations:  Effect of Substrates and Solvent on Chain Formation, Dispersity, and End-Group Structure

, 2016
The effects of substrates and solvent on polymer formation, number-average molecular weight (Mn), polydispersity, and end-group structure for lipase-catalyzed polycondensations were investigated.
Anil Mahapatro (2653129), Bhanu Kalra (2724319), Ajay Kumar (192967), Richard A. Gross (1450531)   +3 more
core   +1 more source

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova, Cicely M. Warne, Hugo Pétremand, Laura König‐Mattern, Johannes Stöckelmaier, Chris Oostenbrink, Georg M. Guebitz, Jeremy Luterbacher, Alessandro Pellis   +8 more
wiley   +1 more source

Lipase-mediated epoxidation of alkenes in supercritical carbon dioxide

, 2018
In this work, supercritical carbon dioxide was used as reaction media in the lipase-mediated epoxidation of alkenes for the first time. Under the optimal conditions (alkene (1 mmol), novozym 435 (15 mg), H2O2 (50% aqueous solution, 1.4 mmol), n-caprylic ...
Wenwei Qian (319259), Liu Zhang, Yang Zhang (30734), Shanshan Chen, Liu Zhang (394571), Shanshan Chen (505293), Jiaxin Zhang, Lei Wang (6656), Chunyu Wang, Yang Zhang, Lei Wang, Ziyi Cao (5948423), Ziyi Cao, Wenwei Qian, Jiaxin Zhang (1836484), Chunyu Wang (459103)   +15 more
core   +1 more source

Stereospecificity of lipases. Enzymic hydrolysis of enantiomeric alkyl diacylglycerols by lipoprotein lipase, lingual lipase and pancreatic lipase [PDF]

FEBS Letters, 1974
Paltauf, F., Esfandi, F., Holasek, A.
openaire   +2 more sources

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang, Viktoria Lahmann, Jan Philipp Bittner, Pablo Domínguez de María, Sven Jakobtorweihen, Irina Smirnova, Selin Kara   +6 more
wiley   +1 more source

HIDROLISIS MINYAK KELAPA DENGAN LIPASE TERIMOBILISASI ZEOLIT PADA PEMBUATAN PERISA ALAMI

Jurnal Bahan Alam Terbarukan, 2016
Free Fatty acid resulting from hydrolisis of various types of oil enzymatically has been great interest recently to save energy, in other hand that the product are environmentally friendly.
Dwina Moentamaria, Girlian Agaian, Meilita Mustika Ridhawati, Achmad Chumaidi, Nanik Hendrawati   +4 more
doaj