Results 1 to 10 of about 880,817 (296)

Proteinaceous Pancreatic Lipase Inhibitor from the Seed of Litchi chinensis [PDF]

Food Technology and Biotechnology, 2019
A study of the pancreatic lipase inhibitory activity of a protein from the seed of Litchi chinensis was carried out. Protein was isolated by 70 % ammonium sulphate precipitation followed by dialysis.
Sveeta V. Mhatre, Amita A. Bhagit, Raman P. Yadav   +2 more
doaj   +3 more sources

Free Linoleic Acid and Oleic Acid Reduce Fat Digestion and Absorption In Vivo as Potent Pancreatic Lipase Inhibitors Derived from Sesame Meal

Molecules, 2022
Pancreatic lipase catalyzes the cleavage of triacylglycerols at the oil–water interface, and is known as the dominant determiner of dietary fat digestion.
Xuan Li, Sayo Morita, Hiroaki Yamada, Keita Koga, Wakana Ota, Toma Furuta, Atsushi Yamatsu, Mujo Kim   +7 more
doaj   +2 more sources

Structure and Function of Pancreatic Lipase-Related Protein 2 and Its Relationship With Pathological States

Frontiers in Genetics, 2021
Pancreatic lipase is critical for the digestion and absorption of dietary fats. The most abundant lipolytic enzymes secreted by the pancreas are pancreatic triglyceride lipase (PTL or PNLIP) and its family members, pancreatic lipase-related protein 1 ...
Guoying Zhu, Guoying Zhu, Qing Fang, Fengshang Zhu, Dongping Huang, Changqing Yang   +5 more
doaj   +2 more sources

Role of pancreatic lipase inhibition in obesity treatment: mechanisms and challenges towards current insights and future directions. [PDF]

Int J Obes (Lond)
The worldwide health emergency of obesity is closely connected to how dietary fats are metabolized, whereas the process is significantly influenced by pancreatic lipase (PL), an enzyme critical for lipid hydrolysis into fatty acids. This narrative review
Subramaniyan V, Hanim YU.
europepmc   +2 more sources

Discovery of Curcuminoids as Pancreatic Lipase Inhibitors from Medicine-and-Food Homology Plants. [PDF]

Nutrients
Researchers are increasingly interested in discovering new pancreatic lipase inhibitors as anti-obesity ingredients. Medicine-and-food homology plants contain a diverse set of natural bioactive compounds with promising development potential.
He XQ, Zou HD, Liu Y, Chen XJ, Atanasov AG, Wang XL, Xia Y, Ng SB, Matin M, Wu DT, Liu HY, Gan RY.   +11 more
europepmc   +2 more sources

Kaempferol inhibits the activity of pancreatic lipase and its synergistic effect with orlistat

Journal of Functional Foods, 2020
Repression of pancreatic lipase activity reduces the excessive absorption of lipids, thereby reducing the risk of being overweight and obese. In the study, the inhibition of kaempferol on pancreatic lipase was studied by various spectroscopy techniques ...
Xing Hu, Guowen Zhang, Guowen Zhang
exaly   +2 more sources

The inhibitory effects of an eight-herb formula (RCM-107) on pancreatic lipase: enzymatic, HPTLC profiling and in silico approaches

Heliyon, 2019
Aims: Obesity is a global, public health issue that causes or exacerbates serious medical disorders. Chinese herbal therapies have become one of the most popular alternatives due to intolerances of current anti-obesity treatments.
Shiqi Luo, Harsharn Gill, Daniel Anthony Dias, Mingdi Li, Andrew Hung, Linh Toan Nguyen, George Binh Lenon   +6 more
doaj   +2 more sources

Combining kinetics and in silico approaches to evaluate bromhexine as an anti-pancreatic lipase agent for obesity management [PDF]

Scientific Reports
Industrialization, fast food intake and reduced physical activity, mainly in developed countries, exacerbate obesity and make it a major lifestyle disorder. A promising strategy for developing effective anti-obesity agents is to inhibit pancreatic lipase,
Asma Gholami, Dariush Minai-Tehrani, Leif A. Eriksson   +2 more
doaj   +2 more sources

QSAR model of pancreatic lipase inhibition by phenolic acids and their derivatives based on machine learning and multi-descriptor strategy

Journal of Agriculture and Food Research, 2023
Inhibition of pancreatic lipase can be effective in controlling or treating obesity. Phenolic acids have good pancreatic lipase inhibitory effects and are widely found in plants.
Yaqi Liu, Fei Pan, Ou Wang, Zehui Zhu, Qing Li, Zicheng Yang, Wenli Tian, Liang Zhao, Lei Zhao   +8 more
doaj   +1 more source

Screening of Anti-Lipase Components of Artemisia argyi Leaves Based on Spectrum-Effect Relationships and HPLC-MS/MS

Frontiers in Pharmacology, 2021
Pancreatic lipase is a key lipase for triacylglyceride digestion and absorption, which is recognized as a promising target for treatment of metabolic disorders. Natural phytochemicals are hopeful sources for pancreatic lipase inhibitors.
Yaqing Chang, Dan Zhang, Guiya Yang, Yuguang Zheng, Yuguang Zheng, Long Guo   +5 more
doaj   +1 more source