Acne vaccine targeting <i>Cutibacterium acnes</i> secretory lipase suppresses the bacteria-induced pro-inflammatory interleukin-6 and macrophage inflammatory protein-2 production. [PDF]
Negari IP +7 more
europepmc +1 more source
ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source
Acute and Chronic Pancreatitis in Mitochondrial Disease: A Systematic Review. [PDF]
Hahl O, Martikainen MH.
europepmc +1 more source
Pancreatic Panniculitis as the First Presentation of Pancreatic Adenocarcinoma
JEADV Clinical Practice, EarlyView.
Claudine Howard‐James +2 more
wiley +1 more source
Liquiritigenin promotes expression of CGI‐58 and enhances lipolysis by down‐regulating expression of PLIN2, thereby facilitating the catabolism of larger‐sized lipid droplets and producing smaller‐sized lipid droplets, resulting in enhanced activity of lipophagy and ameliorated hepatic steatosis. ABSTRACT Metabolic‐associated fatty liver disease (MAFLD)
Zhuoya Xu +7 more
wiley +1 more source
Preclinical Evaluation of Anti-Acne Topical Creams Containing Psorospermum Febrifugum Stem Bark Extract: Lipase Inhibition, Sebum Regulation, and Dermal Safety. [PDF]
Kaweesa SP +6 more
europepmc +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source
Interfacial and Molecular Mechanisms of Pancreatic Lipase Modulation by Saponin-Rich Extracts with Antioxidant Activity. [PDF]
Sroka Z +10 more
europepmc +1 more source
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source

