Results 161 to 170 of about 23,163,981 (284)

Intranasal Delivery of Curcumin-Loaded Pure Drug Self-Assembled Lipid-Based Nanoparticles for Targeted Therapy of Depression. [PDF]

Int J Nanomedicine
Chen T, Liu X, Li D, Cheng Z, Zheng X, Yu Z.   +5 more
europepmc   +1 more source

Precision Localization of Lipid-Based Nanoparticles by Dual-Fluorescent Labeling for Accurate and High-Resolution Imaging in Living Cells. [PDF]

Small Sci, 2023
Huang WQ, Burgers PC, Amin M, Luider TM, Ten Hagen TLM.   +4 more
europepmc   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

Production of Uniform Droplets and Lipid Nanoparticles Using Perfluoropolyether-Based Microfluidic Devices

Microfluidic devices are greatly affected by the materials used. The materials used in previous studies had problems in various aspects, such as processing, adsorption, and price. This study will investigate the materials needed to overcome such problems.
Sung-Wook Choi, Eun Seo Kim, Mincheol Cho, Tae-Kyung Ryu, Inseong Choi   +4 more
core   +1 more source

Biomimetic phycocyanin lipid-based nanoparticles ameliorate placental dysfunction and restore angiogenic balance in a pre-eclampsia model. [PDF]

J Nanobiotechnology
Yuan H, He J, Niu J, Zhou M.
europepmc   +1 more source

ROS‐Targeted Nanomotor Therapy in OA: Cartilage Protection and Pain Relief

Advanced Science, EarlyView.
ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and ...
Meng Zheng, Changyu Liu, Qin Xia, Arndt F. Schilling, Jiawei Jiang, Renpeng Peng, Zixing Shu, Tian Ma, Danni Luo, Yaoyu Zhang, Yibo Fan, Xuyuan Zhang, Song Li, Kai Wang, Wentao Ke, Yuan Xiong, Yuanli Zhu, Fangzhi Mou, Jun Xiao, Hao Zhu   +19 more
wiley   +1 more source

Lipid nanoparticles for topical and transdermal application for alopecia treatment: development, physicochemical characterization, and in vitro release and penetration studies

, 2014
Maria João Gomes,1 Susana Martins,2,3 Domingos Ferreira,2 Marcela A Segundo,1 Salette Reis1 1REQUIMTE, Laboratory of Applied Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, 2Laboratory of Pharmaceutical Technology, Department of ...
Martins S, Gomes MJ, Ferreira D, Segundo MA, Reis S   +4 more
core  

Cationic lipid-based nanoparticles for therapeutic delivery in cancer treatment: physicochemical characteristics, therapeutic cargos, and clinical potential. [PDF]

Appl Microsc
Bae CS, Ahn T.
europepmc   +1 more source

The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability, and Safety of Lipid-Based Nanoparticles for mRNA and DNA Delivery. [PDF]

Adv Healthc Mater, 2023
Kafetzis KN, Papalamprou N, McNulty E, Thong KX, Sato Y, Mironov A, Purohit A, Welsby PJ, Harashima H, Yu-Wai-Man C, Tagalakis AD.   +10 more
europepmc   +1 more source

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

Advanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao, Xinhao Yuan, Shuai Liang, Kai Deng, Daqin Wu, Longhao Xu, Kun Zheng, Yi Lin, Peicong Cai, Haoran Zheng, Junyu Chen, Mingli Luo, Yan Chen, Xiong Chen, Chunhui Wang, Wenlong Zhong   +15 more
wiley   +1 more source