Results 171 to 180 of about 23,163,981 (284)

Using siRNA-Based Anti-Inflammatory Lipid Nanoparticles for Gene Regulation in Psoriasis [PDF]

Aizhong Zeng,* Yuanyuan Liu,* Ping Wang, Yufei Cao, Wei Guo School of Life Science and Technology, China Pharmaceutical University, Nanjing, 211112, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wei ...
Liu Y, Zeng A, Wang P, Cao Y, Guo W
core  

Lipid-based nanoparticles external triggered release strategies in cancer nanomedicine. [PDF]

J Nanobiotechnology
Alhussan A, Ho L, Zhang Y, Fan H, Momeni A, Brimacombe C, Cullis PR.   +6 more
europepmc   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Development of a new class of poly(lipoic acid) nanoparticles as RNA delivery vehicles: the role of the hydrophobic precursors and of the polymeric coating [PDF]

openLipid nanoparticles have attracted significant interest in the last two decades because of their use as drug carriers for both hydrophobic and hydrophilic therapeutics. In particular they seem to be good candidates to deliver nucleic acids, like mRNA
BARBATO, EUGENIA
core  

Lipid-based nanoparticles: advancing therapeutic strategies for vitiligo management. [PDF]

Bioimpacts
Darvishi M, Chekeni AM, Fazelhosseini M, Rajabalizadeh S, Rizwanullah M, Aslam M, Alam MS, Iqbal Z, Mirza MA.   +8 more
europepmc   +1 more source

The Big Potential of Small Particles: Lipid-Based Nanoparticles and Exosomes in Vaccination. [PDF]

Vaccines (Basel), 2022
Shimon MB, Shapira S, Seni J, Arber N.
europepmc   +1 more source

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

Biophysical Characterization of Tolerogenic Lipid-Based Nanoparticles Containing Phosphatidylcholine and Lysophosphatidylserine. [PDF]

J Pharm Sci, 2022
Nguyen NH, Chen M, Chak V, Balu-Iyer SV.
europepmc   +1 more source

Lipid-Based Nanoparticles in Cancer Therapy: Advances in Targeted Drug Delivery and Therapeutic Potential for Renal Cell Carcinoma. [PDF]

Adv Sci (Weinh)
Yao W, Lin Y, Weng Y, Wu Y, Zheng L, Zheng D, Xi Q, Zhao J.   +7 more
europepmc   +1 more source