Results 21 to 30 of about 23,163,981 (284)
OpenNano, 2023 Gemcitabine (GEM) is a chemotherapeutic drug widely used for treating pancreatic cancer and other cancers. Despite its efficacy, GEM is associated with adverse side effects and tumor resistance, hampering its therapeutic outcomes.
Mehrab Pourmadadi +7 more
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Journal of Nanobiotechnology, 2022 Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are
Khaled Mahmoud +3 more
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Lipid-based nanoparticles and RNA as innovative neuro-therapeutics. [PDF]
Front Pharmacol, 2022 RNA-delivery is a promising tool to develop therapies for difficult to treat diseases such as neurological disorders, by silencing pathological genes or expressing therapeutic proteins. However, in many cases RNA delivery requires a vesicle that could effectively protect the molecule from bio-degradation, bypass barriers i.e., the blood brain barrier ...
Tsakiri M +3 more
europepmc +5 more sources
Lipid-Based Nanocarrier Systems for Drug Delivery: Advances and Applications
Pharmaceutical Fronts, 2022 Lipid-based nanocarriers have been extensively investigated for drug delivery due to their advantages including biodegradability, biocompatibility, nontoxicity, and nonimmunogenicity. However, the shortcomings of traditional lipid-based nanocarriers such
Yan-Qi Zhao +6 more
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Studies of PLGA Nanoparticles for Pharmaceutical Applications [PDF]
, 2014 PLGA have already been successfully applied for controlled drug delivery systems by the pharmaceutical industry due to its biocompatibility, biodegradability and ease of processing.
Sun, Yanqi
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Lipid-based nanoparticle production in Micromixers [PDF]
Proceedings of Micromachines 2021 — 1st International Conference on Micromachines and Applications (ICMA2021), 2021 Lipid-based nanoparticles have demonstrated to be a versatile vehicle for drugs, genetic material, and labels. These particles are often made of biocompatible and biodegradable materials, enabling a safe interaction with biological systems. The importance of this type of delivery vehicle has been shown recently, as the two leading vaccines are based on
Vahé Nerguizian, Rodrigo Lopez Salazar
openaire +1 more source
Microfluidic Devices for Precision Nanoparticle Production
Micro, 2023 In recent years, the field of drug delivery has seen a significant shift towards the exploration and utilization of nanoparticles (NPs) as versatile carriers for therapeutic agents.
Ayşenur Bezelya +2 more
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Hybrid Magnetic Lipid-Based Nanoparticles for Cancer Therapy. [PDF]
Pharmaceutics, 2023 Cancer is one of the major public health problems worldwide. Despite the advances in cancer therapy, it remains a challenge due to the low specificity of treatment and the development of multidrug resistance mechanisms. To overcome these drawbacks, several drug delivery nanosystems have been investigated, among them, magnetic nanoparticles (MNP ...
Luiz MT +5 more
europepmc +4 more sources
Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R +3 more
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, 2021 Emerging therapeutic treatments based on the production of proteins by delivering mRNA have become increasingly important in recent times. While lipid nanoparticles (LNPs) are approved vehicles for small interfering RNA delivery, there are still ...
core +1 more source