Results 31 to 40 of about 23,163,981 (284)

Effect of size, shape, and surface modification on cytotoxicity of gold nanoparticles to human Hep-2 and canine MDCK cells [PDF]

, 2012
There have been increasing interests in applying gold nanoparticles in biological research, drug delivery, and therapy. As the interaction of gold nanoparticles with cells relies on properties of nanoparticles, the cytotoxicity is complex and still under
Li, Wenqin, Xu, Dan, Chen, Yu, Zhang, Yinan, Yu, Jun   +4 more
core   +4 more sources

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Structure, Preparation and Application [PDF]

Advanced Pharmaceutical Bulletin, 2015
Lipid nanoparticles (LNPs) have attracted special interest during last few decades. Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.
Neda Naseri, Hadi Valizadeh, Parvin Zakeri-Milani   +2 more
doaj   +1 more source

A comparative biodistribution study of polymeric and lipid-based nanoparticles. [PDF]

Drug Deliv Transl Res, 2022
AbstractBiodistribution of nanoencapsulated bioactive compounds is primarily determined by the size, shape, chemical composition and surface properties of the encapsulating nanoparticle, and, thus, less dependent on the physicochemical properties of the active pharmaceutical ingredient encapsulated.
Åslund AKO, Vandebriel RJ, Caputo F, de Jong WH, Delmaar C, Hyldbakk A, Rustique E, Schmid R, Snipstad S, Texier I, Vernstad K, Borgos SEF.   +11 more
europepmc   +6 more sources

Lipid Nanoparticles Loaded with Iridoid Glycosides: Development and Optimization Using Experimental Factorial Design

Molecules, 2021
Lipid nanoparticles based on multiple emulsion (W/O/W) systems are suitable for incorporating hydrophilic active substances, including iridoid glycosides.
Marta Dąbrowska, Eliana B. Souto, Izabela Nowak   +2 more
doaj   +1 more source

Lipid-Based Nanoparticles

Journal of Innovations in Applied Pharmaceutical Science (JIAPS)
Lipid-based nanoparticles (LNPs) are nano-sized particles composed of lipids, which are natural or synthetic molecules. It comprises of phospholipid bilayer in its structure. The unique properties of lipids such as biocompatibility and versatility, have spurred the development of various lipid based nano formulations.
Sindhu Gillella, Rishitha S, Divyanjali M, Amzad SK, Anu B, Girish C, Apparao CH   +6 more
openaire   +2 more sources

Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles [PDF]

Pharmaceutics, 2021
Messenger RNA (mRNA) is being extensively used in gene therapy and vaccination due to its safety over DNA, in the following ways: its lack of integration risk, cytoplasmic expression, and transient expression compatible with fine regulations. However, clinical applications of mRNA are limited by its fast degradation by nucleases, and the activation of ...
Delehedde, Christophe, Even, Luc, Midoux, Patrick, Pichon, Chantal, Perche, Federico   +4 more
openaire   +4 more sources

Efficient chemotherapy of rat glioblastoma using Doxorubicin-loaded PLGA nanoparticles with different stabilizers [PDF]

, 2011
Background: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain.
Markus Glatzel, Kreuter, Jörg (Prof. Dr.), Christian Bernreuther, Olga Maksimenko, Maksimenko, Olga, Khalansky, Alexander S., Jörg Kreuter, Wohlfart, Stefanie, Gelperina, Svetlana, Svetlana Gelperina, Bernreuther, Christian, Stefanie Wohlfart, Alexander S Khalansky, Glatzel, Markus, Alexander S. Khalansky   +14 more
core   +2 more sources

Therapeutic peptides and their delivery using lipid-based nanoparticles. [PDF]

Tzu Chi Med J
ABSTRACT Therapeutic peptides have become an intensively anticipated research field for novel drug discovery and design owing to their high specificity, efficacy, and biocompatibility. The advances in computer technology and structural biology, together with the invention of chemical peptide synthesis methods, have ...
Yen JH, Chang CC, Wu TY, Yang CH, Hsu HJ, Liou JW.   +5 more
europepmc   +4 more sources

The effect of virgin coconut oil loaded solid lipid particles (VCO-SLPs) on skin hydration and skin elasticity [PDF]

, 2013
Virgin Coconut Oil is usually extracted from well matured and fresh coconut through specialized processes without damaging its natural nutrition. In this work, formulation, characterization and efficacy of VCO-SLPs have been studied.
Sarmidi, Mohamad Roji, Mohamed Noor, Norhayati, Abd. Aziz, Azila, Aziz, Ramlan   +3 more
core   +1 more source

Impact of Citrate and Lipid-Functionalized Magnetic Nanoparticles in Dehydropeptide Supramolecular Magnetogels: Properties, Design and Drug Release

Nanomaterials, 2020
Currently, the nanoparticle functionalization effect on supramolecular peptide-based hydrogels remains undescribed, but is expected to affect the hydrogels’ self-assembly and final magnetic gel properties.
Sérgio R. S. Veloso, Joana F. G. Silva, Loic Hilliou, Cacilda Moura, Paulo J. G. Coutinho, José A. Martins, Martín Testa-Anta, Verónica Salgueiriño, Miguel A. Correa-Duarte, Paula M. T. Ferreira, Elisabete M. S. Castanheira   +10 more
doaj   +1 more source