Results 51 to 60 of about 23,163,981 (284)

C34 Formulation of shea butter-based lipid nanoparticles for topical and transdermal applications

Journal Africain de Technologie Pharmaceutique et Biopharmacie, 2023
Introduction: Shea butter is a natural lipid widely used in topical formulations because of its hydrating, anti-inflammatory and regenerative properties on the skin.
B. Gérard Josias YAMEOGO, Carmen F. W. KABORE, B. Charles SOMBIE, Hermine ZIME DIAWARA, Denis WOUESSIDJEWE, Rasmané SEMDE, Annabelle GEZE   +6 more
doaj   +1 more source

Intranasal agomelatine solid lipid nanoparticles to enhance brain delivery: formulation, optimization and in vivo pharmacokinetics [PDF]

, 2017
Ahmed M Fatouh,1 Ahmed H Elshafeey,1,2 Ahmed Abdelbary1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2School of Pharmacy, University of Waterloo, Waterloo, ON, Canada Purpose: Agomelatine is
Ahmed Fatouh, Fatouh AM, Abdelbary A, Elshafeey AH, Ahmed Abdelbary, Ahmed Elshafeey   +5 more
core   +1 more source

Phase‐Separated Lipid‐Based Nanoparticles: Selective Behavior at the Nano‐Bio Interface

Advanced Materials, 2023
AbstractThe membrane‐protein interface on lipid‐based nanoparticles influences their in vivo behavior. Better understanding may evolve current drug delivery methods toward effective targeted nanomedicine. Previously, the cell‐selective accumulation of a liposome formulation in vivo is demonstrated, through the recognition of lipid phase‐separation by ...
Papadopoulou, P., Pol, R. van der, Hilten, N. van, Os, W.L. van, Pattipeiluhu, R., Arias Alpizar, G., Knol, R.A., Noteborn, W., Moradi, M., Joao Ferraz, M., Aerts, J.M.F.G, Sommerdijk, N.A.J.M., Campbell, F., Risselada, H.J., Sevink, G.J.A., Kros, A.   +15 more
openaire   +6 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

DBT degradation enhancement by decorating Rhodococcus erythropolis IGST8 with magnetic Fe3O4 nanoparticles [PDF]

, 2009
Biodesulfurization (BDS) of dibenzothiophene (DBT) was carried out by Rhodococcus erythropolis IGST8 decorated with magnetic Fe3O4 nanoparticles, synthesized in-house by a chemical method, with an average size of 45-50 nm, in order to facilitate the post-
Ansari, Farahnaz, Libor, Zsuzsanna, Grigoriev, P., Ramsden, Jeremy J., Tothill, Ibtisam E.   +4 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Preparation of Nanoparticles of Digoxin Solid Lipid

Chemical Engineering Transactions, 2017
In order to prove the role of solid lipid nanoparticles in oral absorption and bioavailability, the biodegradable monoglyceride with low toxicity and good biocompatibility is used as lipid materials to prepare nanoparticles of digoxin solid lipid and ...
Ping Luo, Yangwu Liu
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Lipid nanoparticles: A challenging approach for oral delivery of BCS Class-II drugs

Future Journal of Pharmaceutical Sciences, 2018
In today's drug development world, combinatorial chemistry, high-throughput screening, and genomics have provided a technologic platform that produces a large number of new chemical entities with therapeutic potential each year.
Ganesan Poovi, Narayanasamy Damodharan
doaj   +1 more source