Results 61 to 70 of about 23,163,981 (284)

Curcumin Nanoparticles and Their Cytotoxicity in Docetaxel-Resistant Castration-Resistant Prostate Cancer Cells

open access: yesBiomedicines, 2020
Most prostate cancer patients develop resistance to anti-androgen therapy. This is referred to as castration-resistant prostate cancer (CRPC). Docetaxel (DTX) is the mainstay treatment against CRPC.
Irin Tanaudommongkon   +5 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Lipid-Based Nanoparticles in Cancer Diagnosis and Therapy [PDF]

open access: yesJournal of Drug Delivery, 2013
Today, researchers are constantly developing new nanomaterials, nanodevices, and nanoparticles to meet unmet needs in the delivery of therapeutic agents and imaging agents for cancer therapy and diagnosis, respectively. Of particular interest here are lipid-based nanoparticles (LNPs) that are genuine particles (approximately 100 nm in dimension ...
openaire   +2 more sources

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Development of solid lipid nanoparticles by microfluidic technique for oral delivery of peptides

open access: yes, 2022
reservedThis thesis project was aimed to develop solid lipid nanoparticles (SLNs) based formulation for the oral delivery of a model peptide. In order to obtain a reproducible and scalable formulation process, microfluidic technology (Nanoassembler ...
SQUIZZATO, BEATRICE
core  

Electrodynamic droplet actuation for lab on a chip system

open access: yes, 2011
This work presents the development of electrowetting on dielectric and liquid dielectrophoresis as a platform for chemistry, biochemistry and biophysics.
Aghdaei, Sara
core   +1 more source

Novel resveratrol nanodelivery systems based on lipid nanoparticles to enhance its oral bioavailability

open access: yesInternational Journal of Nanomedicine, 2013
Ana Rute Neves,1 Marlene Lúcio,1 Susana Martins,2,3 José Luís Costa Lima,1 Salette Reis11REQUIMTE, Chemistry Department, Faculty of Pharmacy, University of Porto, 2Laboratory for Pharmaceutical Technology/Research Centre ...
Neves AR   +4 more
doaj  

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

open access: yesBeilstein Journal of Nanotechnology, 2019
This investigation is a study of new lipid nanoparticles for cutaneous antioxidant delivery. Several molecules, such as α-tocopherol and retinoic acid, have been shown to improve skin condition and even counteract the effects of exogenous stress factors ...
Elisabetta Esposito   +7 more
doaj   +1 more source

Cyclodextrin-Based Nanosponges as Novel Approach for Drug Delivery. [PDF]

open access: yesRecords of Pharmaceutical & Biomedical Sciences
Over the last two decades, the drug delivery market has witnessed the advent of nanotechnology. Nanotechnology involves developing and applying chemical, physical, and biological systems characterized by structures ranging from single atoms or molecules ...
Shadeed Gad, Marwa zaima, Hani Mahmoud
doaj   +1 more source

Lipid-based nanoparticles as novel drug delivery systems for antimicrobial agents [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2018
Despite the development of novel drugs and technologies in combating the infectious diseases, they remain as a global health challenge. The use of conventional antimicrobial drugs are always associated with problems such as antimicrobial resistance ...
Ali Rassouli, Alwan Al-Qushawi
doaj   +1 more source

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