Results 91 to 100 of about 158,005 (297)
Lipid-lowering therapies: Better together [PDF]
Atherosclerosis, 2021 Maciej Banach, Peter E. Penson
openaire +2 more sources
Lipid-lowering therapy: strategies for improving compliance
, 2004 Lowering cholesterol levels is a primary approach for reducing the risk of coronary heart disease (CHD), yet patients rarely achieve the lipid targets recommended by international guidelines.
Noll, G +8 more
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Advanced Science, EarlyView.Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen +14 more
wiley +1 more source
Рациональная фармакотерапия в кардиологии, 2018 Aim. To estimate the prevalence of familial hypercholesterolemia (FH) in a sample of Moscow city and Moscow region patients with hypercholesterolemia (HCh) based on lipid spectrum and instrumental methods.Material and methods.
I. V. Sergienko, A. A. Ansheles
doaj +1 more source
Adherence to lipid-lowering treatment: the patient perspective
, 2012 Manuela Casula,1 Elena Tragni,1 Alberico Luigi Catapano1,21Epidemiology and Preventive Pharmacology Centre (SEFAP), Department of Pharmacological Sciences, University of Milan, Milan, Italy; 2IRCCS MultiMedica, Sesto San Giovanni, ItalyAbstract: Despite ...
Casula M, Tragni E, Catapano AL
core
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
Advanced Science, EarlyView.We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
Клинический разбор в общей медицинеThe aim. Study the effect of combined lipid-lowering therapy (statins+ezetimibe+Inclisiran) for left ventricular (LV) myocardial cell perfusion in patients with severe lipid metabolism disorders according to single-photon emission computed tomography ...
Natalia S. Kurochkina +10 more
doaj +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Lipid-lowering therapy in a real-world setting : eligibility, utilization, and goal attainment
IntroductionLow-density lipoprotein cholesterol (LDL-C), and other lipid fractions containing apolipoprotein B, have been identified as key components in the process of atherogenesis and consequently the progression to cardiovascular disease (CVD ...
Ali Yari (18656374)
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Advanced Science, EarlyView.Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source