Results 101 to 110 of about 158,005 (297)

Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008 [PDF]

, 2014
Aim: To describe characteristics associated with statin prescribing for the primary prevention of cardiovascular disease in people with newly diagnosed diabetes.
Scottish Diabetes Research Network (SDRN) Epidemiology group, Wild, S H, Sattar, N, Sattar, N., Jones, N R V, Wild, S.H., Wild, S. H., McKnight, J. A., Fischbacher, C M, Pearson, D, Fischbacher, C. M., Leese, G, Lindsay, R.S, Leese, G., McKnight, J.A., Philip, S, Fischbacher, C.M., ?, ?, Lindsay, R. S., Pearson, D., Jones, N. R. V., Guthrie, B, Lindsay, R S, Philip, S., Jones, N.R.V., Guthrie, B., McKnight, J A, Wild, S H; id_orcid   +27 more
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

CENTRALISED SURVEY ON THE UNDERTREATMENT OF THE HYPERCHOLESTEROLEMIA IN RUSSIA (CEPHEUS)

Кардиоваскулярная терапия и профилактика, 2013
Aim. To assess the percentage of the patients who receive lipid-lowering drug therapy and achieve target levels of low-density lipoprotein cholesterol (LDL–CH), in accordance with the recommendations by the Russian Cardiology Society (RCS) and the 4th ...
S. A. Boytsov, Yu. V. Khomitskaya
doaj   +1 more source

Ezetimibe is effective when added to maximally tolerated lipid lowering therapy in patients with HIV [PDF]

, 2007
To determine the efficacy and safety of adding ezetimibe to maximally tolerated lipid lowering therapy in patients with HIV dyslipidemia. Retrospective analysis of lipid parameters was conducted for 33 patients with HIV who had been prescribed ezetimibe ...
Kevin W Johns, Bondy Gregory P, Matthew T Bennett, Gregory P Bondy, Matthew T Bennett, Bennett Matthew T, Johns Kevin W   +6 more
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Lipid-lowering therapy in older persons.

Archives of medical science : AMS, 2015
Numerous randomized, double-blind, placebo-controlled studies and observational studies have shown that statins reduce mortality and major cardiovascular events in older high-risk persons with hypercholesterolemia. The Heart Protection Study showed that statins reduced mortality and major cardiovascular events in high-risk persons regardless of the ...
openaire   +2 more sources

Assessing the benefits of lipid-lowering therapy

The American Journal of Cardiology, 1998
In recent years, a substantial body of evidence has emerged to support the use of lipid-lowering therapy in the prevention of coronary artery disease, and many physician groups have endorsed the management of dyslipidemia in at-risk patients. An important consideration in such endorsements has been the issue of the safety of lipid intervention; many ...
openaire   +2 more sources

Lipid Lowering Therapy: An Era Beyond Statins.

, 2022
Dyslipidemia, specifically elevated LDL cholesterol levels, causes atherosclerotic cardiovascular disease (ASCVD) and increases the risk of myocardial infarction and stroke.
Shah, Rohan, Patel, Neal, Corriero, Anna, Mares, Adriana C, Awuah, Wireko Andrew, Shaikh, Raheel, Capriles, Camilo Andrés Avendaño, Abdul-Rahman, Toufik, Bukhari, Syed Muhammad Awais, Herrera, Emiliano Cantu, de Andrade, Heloisa, Ahmad, Shahzaib, Gupta, Rahul, MD, Goel, Akshay, Lawrence, Jannel, Ulusan, Sebahat, Hajra, Adrija, Bandyopadhyay, Dhrubajyoti   +17 more
core  

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source