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Real-world changes in lipid-lowering therapy use and LDL-C goal attainment in high and very high cardiovascular risk patients in the UK: a secondary analysis of the European SANTORINI study 1-year follow-up. [PDF]
Connolly D +9 more
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Medication persistence trajectories among individuals prescribed lipid-lowering therapy in primary care settings: A retrospective cohort study. [PDF]
Orman Z +12 more
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LDL-cholesterol control in high-risk individuals: an international obstacle and call for earlier combination lipid-lowering therapy. [PDF]
Razavi AC, Sokolsky M, Blumenthal RS.
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Aortopathy: Effects of Lipid-Lowering Therapy
Cardiology in Review, 2023Aortopathies can be congenital or acquired. Aortic atherosclerosis, abdominal aortic aneurysm, and degenerative aortic stenosis are some of the major manifestations of acquired aortopathy. Dyslipidemia, an imbalance of plasma lipid levels, is strongly associated with common aortopathies.
Matthew, Vollaro +4 more
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New and Emerging lipid-lowering Therapy
Future Cardiology, 2021Statins remain the drugs of choice in patients at risk of or with atherosclerotic cardiovascular disease (ASCVD). Statins have limitations that drive the development of investigational agents to manage dyslipidemias and/or reduce ASCVD risk. There are a few small-molecule drugs that have the potential to mitigate ASCVD risk either alone or in ...
James M, Backes, Daniel E, Hilleman
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Pharmacogenetics of lipid-lowering therapies
Current Atherosclerosis Reports, 2002Cardiovascular disease is associated with nonmodifiable risk factors such as age, gender, and genetic background, and with modifiable risk factors such as lipid concentrations. Lowering serum lipid levels has been demonstrated to slow the progression of, or even induce regression in, atherosclerosis.
Jose M, Ordovas, Haiqing, Shen
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