Results 141 to 150 of about 1,333,166 (267)

Enhancing and Stabilizing Hydrogen Catalysis Through [NiFe]‐Hydrogenase Immobilization Within Macroporous Covalent Organic Frameworks

open access: yesAdvanced Functional Materials, EarlyView.
[NiFe]‐hydrogenases efficiently catalyze hydrogen conversion, but their instability limits biotechnological applications. Here it is shown that encapsulating hydrogenase into hierarchical COFs with macro‐ and micropores and functionalized with sulfonic or carboxylic acid groups improves enzyme stability and electron transfer to electrodes.
Islam E. Khalil   +12 more
wiley   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang   +13 more
wiley   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Gut microbiota, lipid metabolism, and PCOS: A Mendelian randomization and mediation analysis. [PDF]

open access: yesMedicine (Baltimore)
Li W   +10 more
europepmc   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava   +7 more
wiley   +1 more source

2025 Egyptian guidelines for the management of dyslipidemia. [PDF]

open access: yesEgypt Heart J
Reda A   +9 more
europepmc   +1 more source

Living Liquid Metal Composites Embedded with Electrogenic Endospores for Next‐Generation Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
A new class of living liquid metal composites is introduced, embedding Bacillus subtilis endospores into eutectic gallium–indium (EGaIn). The spores enhance droplet coalescence, strengthen interfacial conductivity, and provide on‐demand electrogenic functionality after germination. The composites exhibit high conductivity, self‐healing, patternability,
Maryam Rezaie, Yang Gao, Seokheun Choi
wiley   +1 more source

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