Results 191 to 200 of about 1,333,166 (267)

KIF13B Attenuates Sepsis-Induced Myocardial Dysfunction through the Stabilization of PLIN5. [PDF]

Research (Wash D C)
Zhang L, Miao G, Mei S, Han Y, Xu Y, Zhang W, Chen J, Lu K, Zhao Y, Zhou Z, Chen J, Guo J, Lai P, Lam SM, Shui G, Zhang L, Zhang W, Huang W, Wang Y, Xian X.   +19 more
europepmc   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Feasibility of salivary lipid screening for caries biomarkers in young adults. [PDF]

BMC Oral Health
Li Z, Zhang K, Wang D, Hu J, Liu S, Xu L.   +5 more
europepmc   +1 more source

Metallofullerenol Sc3N@C80(OH)18: A New Generation Radioprotector Protecting Human Erythrocytes Against Multiple Biochemical Damage Modes Upon Gamma Irradiation, Identifying It as a Scavenger of Short‐ and Long‐Lived Radicals

Advanced Healthcare Materials, EarlyView.
Metallofullerenol Sc3N@C80(OH)18 demonstrates strong radioprotective properties as a scavenger of both short‐ and long‐lived radicals. The study reveals protection of human erythrocytes from γ‐radiation–induced biochemical damage via post‐irradiation removal of primary and secondary reactive oxidants, supported by pulse radiolysis kinetics.
Jacek Grebowski, Maciej Studzian, Szymon Lekki‐Porebski, Anna Konarska, Marian Wolszczak, Grzegorz Litwinienko, Lukasz Pulaski   +6 more
wiley   +1 more source

The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis. [PDF]

Nat Commun
Meng F, Du Y, Liang J, Li H, Wang J, Tang K, Kong R, Sun H, Yin T, Qin J, Yang X, Shan C, Liu M, Yang G, Zhang J, Wang Y, Zhou J, Chen Y.   +17 more
europepmc   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

CES3 promotes NSCLC progression via lipid metabolic reprogramming regulated by TFAP2A. [PDF]

J Cancer
Luo P, Huang Z, Ding S, Tang Z, Wei Y, Jiang S, Tang R, Li F, Yang H, Zhao L.   +9 more
europepmc   +1 more source

Assembling Lipid Membrane Scaffolds on Microgel-Based Artificial Cells through Vesicle Fusion onto the Hydrogel Network. [PDF]

ACS Nano
Allen ME, Hindley JW, Müller MI, Cai K, Kuimova MK, Law RV, Connell SD, Wegner SV, Ces O, Elani Y.   +9 more
europepmc   +1 more source

CircZBTB46 alleviates metabolic dysfunction-associated steatotic liver disease by targeting miRNA-326/FGF1 axis. [PDF]

Cell Death Discov
Zeng QM, Hu T, Jiang W, Teng X, Wu D, Tang H, Liu CH.   +6 more
europepmc   +1 more source

Lipid metabolism abnormalities in pediatric abdominal solid malignant tumors: a comprehensive review. [PDF]

Front Pediatr
Hao Q, Han L, Mi W, Hu T, Lin A, Liu J.
europepmc   +1 more source