Results 21 to 30 of about 2,544,846 (305)

Lateral phase separation in mixtures of lipids and cholesterol [PDF]

, 2004
In an effort to understand "rafts" in biological membranes, we propose phenomenological models for saturated and unsaturated lipid mixtures, and lipid-cholesterol mixtures.
Bloom M., D Andelman, Dietrich C., Feigenson G. W., H Shirotori, Kessel A., Lawrence J. C., Lipowsky R., Lipowsky R., Nielsen M., P. D Olmsted, Pandit S. A., Priest R. G., S Komura, Sackmann E., Veatch S. L., Yuan C.   +16 more
core   +2 more sources

Charge-induced phase separation in lipid membranes [PDF]

, 2014
The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of ...
Andelman, David, Hamada, Tsutomu, Himeno, Hiroki, Komura, Shigeyuki, Shimokawa, Naofumi, Takagi, Masahiro   +5 more
core   +2 more sources

Incorporation of cytochrome oxidase into cardiolipin bilayers and induction of nonlamellar phases. [PDF]

, 1990
Cytochrome oxidase from beef heart has been lipid-substituted with beef heart cardiolipin. The lipid phase behavior and protein aggregation state of the reconstituted complexes have been studied with 31P NMR, freeze-fracture electron microscopy, and ...
Knowles, P., Marsh, D., Powell, G.
core   +2 more sources

The Serine Hydrolase ABHD6 Is a Critical Regulator of the Metabolic Syndrome

Cell Reports, 2013
The serine hydrolase α/β hydrolase domain 6 (ABHD6) has recently been implicated as a key lipase for the endocannabinoid 2-arachidonylglycerol (2-AG) in the brain.
Gwynneth Thomas, Jenna L. Betters, Caleb C. Lord, Amanda L. Brown, Stephanie Marshall, Daniel Ferguson, Janet Sawyer, Matthew A. Davis, John T. Melchior, Lawrence C. Blume, Allyn C. Howlett, Pavlina T. Ivanova, Stephen B. Milne, David S. Myers, Irina Mrak, Vera Leber, Christoph Heier, Ulrike Taschler, Jacqueline L. Blankman, Benjamin F. Cravatt, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Robert Zimmermann, H. Alex Brown, J. Mark Brown   +25 more
doaj   +1 more source

Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. [PDF]

, 2018
Lipidomics - the global assessment of lipids - can be performed using a variety of mass spectrometry (MS)-based approaches. However, choosing the optimal approach in terms of lipid coverage, robustness and throughput can be a challenging task.
Brunet, Anne, Contrepois, Kévin, Hornburg, Daniel, Mahmoudi, Salah, Papsdorf, Katharina, Snyder, Michael, Ubhi, Baljit K   +6 more
core   +3 more sources

Physicochemical characterization of biological and synthetic forms of two lipid A-based TLR4 agonists

Heliyon, 2023
Toll-like receptor (TLR) agonists are recognized as potential immune-enhancing adjuvants and are included in several licensed vaccines. Monophosphoryl lipid A (MPL®, GlaxoSmithKline) is one such TLR4 agonist that has been approved for use in human ...
Gang Hu, David J. Varisco, Sayan Das, C. Russell Middaugh, Francesca Gardner, Robert K. Ernst, Wendy L. Picking, William D. Picking   +7 more
doaj   +1 more source

Coupling between pore formation and phase separation in charged lipid membranes [PDF]

, 2015
We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids.
Hamada, Tsutomu, Higuchi, Yuji, Himeno, Hiroki, Ito, Hiroaki, Shimokawa, Naofumi, Takagi, Masahiro   +5 more
core   +2 more sources

Effect of charged lipids on the ionization behavior of glutamic acid containing transmembrane helices [PDF]

, 2020
Transmembrane proteins make up critical components of living cells. Protein function can be greatly impacted by the charged state of its respective components, the side chains of amino acid residues.
Nunn, Brooke
core   +2 more sources

CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization[S]

Journal of Lipid Research, 2015
CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under basal conditions, preventing interaction with ATGL. Upon activation of protein kinase A (PKA), perilipin 1A is phosphorylated
Anita Sahu-Osen, Gabriela Montero-Moran, Matthias Schittmayer, Katarina Fritz, Anna Dinh, Yu-Fang Chang, Derek McMahon, Andras Boeszoermenyi, Irina Cornaciu, Deanna Russell, Monika Oberer, George M. Carman, Ruth Birner-Gruenberger, Dawn L. Brasaemle   +13 more
doaj   +1 more source

Interactions between lipid source and vitamin A on broiler performance, blood parameters, fat and protein deposition rate, and bone development

Poultry Science, 2021
A total of 2622 male broilers were distributed in a 2 × 5 factorial design, using 2 lipid sources (soybean oil and palm fat), 5 levels of vitamin A supplementation (0, 3,000, 6,000, 12,000, and 24,000 IU kg−1), with 10 replicates, and also 1 control diet
V.D.L. Savaris, C. Souza, L. Wachholz, J. Broch, C. Polese, P.L.O. Carvalho, P.C. Pozza, C. Eyng, R.V. Nunes   +8 more
doaj   +1 more source