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Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK.

Cell Metabolism
The accumulation of lipid droplets (LDs) in aging and Alzheimer's disease brains is considered a pathological phenomenon with unresolved cellular and molecular mechanisms. Utilizing stimulated Raman scattering (SRS) microscopy, we observed significant in
Yajuan Li   +11 more
semanticscholar   +1 more source

Enhanced extracellular lipid accumulation in acidic environments

Current Opinion in Lipidology, 2006
Binding of apolipoprotein B-100-containing lipoproteins (VLDL, IDL, and LDL) to proteoglycans and modifications of the lipoproteins, whether bound or unbound, are key processes in atherogenesis. The complex interplay between binding and modification has been studied at neutral pH conditions.
Katariina, Oörni, Petri T, Kovanen
openaire   +2 more sources

The effect of stress environment towards lipid accumulation in microalgae after harvesting

, 2020
Microalgae have been recognized as a potential feedstock for biodiesel production due to their fast growth rate and ability to accumulate lipid within their cells.
Zhia Lerc Poh   +7 more
semanticscholar   +1 more source

Effects of microplastics on growth, phenanthrene stress, and lipid accumulation in a diatom, Phaeodactylum tricornutum.

Environmental Pollution, 2019
Most laboratory studies have focused on the effects of nanoplastics instead of plastics at the micrometer scale, which are the major microplastics (MPs) discarded in marine environments.
Yahong Guo   +8 more
semanticscholar   +1 more source

Lipids easy to accumulate in the liver and lipids hard to accumulate in it

Nutrition Research, 1997
Abstract Accumulation of lipids in the liver, fatty acid composition and molecular species of serum and hepatic triglycerides were investigated after rats were raised for 4 weeks with diets containing beef powder and 12% level of various lipids. Some diagnostic parameters in the serum and acetyl-CoA carboxylase and peroxisomal β-oxidation activities ...
Satoshi Kawahara   +4 more
openaire   +1 more source

Enhanced microalgal growth and lipid accumulation by addition of different nanoparticles under xenon lamp illumination.

Bioresource Technology, 2019
In this study, the growth and lipid accumulation of Scenedesmus sp. using different nanoparticles and light sources were investigated. Xenon lamp can produce a broad illumination spectrum, and exhibited better performance than light-emitting diode.
H. Ren   +7 more
semanticscholar   +1 more source

PM2.5 aggravates the lipid accumulation, mitochondrial damage and apoptosis in macrophage foam cells.

Environmental Pollution, 2019
Epidemiological evidence showed that the particulate matter exposure is associated with atherosclerotic plaque progression, which may be related to foam cell formation, but the mechanism is still unknown.
Jiangyan Liu   +9 more
semanticscholar   +1 more source

Curcuma wenyujin rhizomes extract ameliorates lipid accumulation

Fitoterapia
Curcuma wenyujin (C. wenyujin) is a medicinal plant that is traditionally used to treat blood stagnation, liver fibrosis, pain, and jaundice. In this study, we examined the effect of C. wenyujin rhizome extract on hepatic lipid accumulation both in vivo and in vitro. We found that the petroleum ether fraction of C.
Hong, Wang   +5 more
openaire   +2 more sources

ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts

American Journal of Physiology-Endocrinology and Metabolism, 2002
Adipose differentiation-related protein (ADRP) is a lipid droplet-associated protein that is expressed early during adipose differentiation. The present study was undertaken to reveal the role of ADRP in adipose differentiation. In murine fibroblasts infected with green fluorescent protein (GFP)-ADRP fusion protein expression adenovirus vector ...
Minako, Imamura   +6 more
openaire   +2 more sources

Enhancement of lipid accumulation in microalgae by metabolic engineering.

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2019
Microalgal lipids have drawn great attention as a promising sustainable resource for biodiesel or food supplement production. The development of high-performance strains of microalgae by metabolic engineering is invaluable for increasing the quantity or ...
Xiaoman Sun   +4 more
semanticscholar   +1 more source

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