Results 111 to 120 of about 219,006 (336)

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Lamellar and inverse micellar structures of skin lipids: Effect of templating [PDF]

, 2014
The outermost layer of skin, the stratum corneum (SC), comprises rigid corneocytes in a layered lipid matrix. Using atomistic simulations we find that the equilibrium phase of the SC lipids is inverse micellar.
Das, Chinmay, Noro, Massimo G., Olmsted, Peter D.   +2 more
core   +1 more source

Battery‐Free, Wireless Multi‐Sensing Platform for Comprehensive Management of Pressure Injury and Hygiene

Advanced Functional Materials, EarlyView.
A battery‐free, wireless device for real‐time monitoring of pressure injury and hygiene integrates pressure (≈10 kPa), temperature (≈40 °C), and NH3 gas sensing with antibacterial functionality. Enabled by near‐field communication, it ensures simultaneous, interference‐free mechanical and chemical monitoring, offering a practical solution for pressure ...
Myungwoo Choi, Sunwoo Lee, Sang Won Kim, Ji Yeon Lee, Younghan Kim, Jewook Kim, Gye Hyeon Lee, Saehan Choi, Seonggwang Yoo, Hak‐Young Ahn, Taehoon Kim, Je‐Sang Lee, Weon Gi Min, Inkyu Park, Young‐Seok Shim, Yoon Sung Nam, Seokwoo Jeon, Jeong‐O Lee, Yong Suk Oh, Donghwi Cho   +19 more
wiley   +1 more source

Molecular Dynamics Investigation of Lipid-Specific Interactions with a Fusion Peptide

Biomolecules
The HIV-1 fusion peptide, which is a short hydrophobic peptide from the gp41 coat glycoprotein that participates in the infection of a cell, interacts with model lipid bilayer membranes in a concentration-dependent manner.
William T. Heller
doaj   +1 more source

Investigating Interactions of Biomembranes and Alcohols: A Multiscale Approach

, 2004
We study the interaction of lipid bilayers with short chain alcohols using molecular dynamics on different length scales. We use detailed atomistic modeling and modeling on the length scale where an alcohol is just an amphiphilic dimer.
Adachi, Ayton, Balali-Mood, Bandyopadhyay, Bemporad, Berendsen, Berendsen, Berger, Bisson, Cramer, de Vries, Essmann, Falck, Faller, Feller, Feller, Goetz, Guo, Gurtovenko, Husslein, Kranenburg, Lee, Leontiadou, Lindahl, Ly, Ly, Marrink, Marrink, Mashl, Mou, Mouritsen, Müller, Nagle, Pandit, Pandit, Patra, Patra, Patra, Pereira, Rog, Saiz, Shelley, Smit, Smondryev, Smondryev, Soddemann, Sum, Sum, Tieleman, Tobias, Tu   +50 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Examination of the Interaction between a Membrane Active Peptide and Artificial Bilayers by Dual Polarisation Interferometry

Bio-Protocol, 2017
Examining the interaction of peptides with lipid bilayers to determine binding kinetics is often performed using surface plasmon resonance (SPR). Here we describe the technique of dual polarisation interferometry (DPI) that provides not only information ...
Jennifer Payne, Tzong-Hsien Lee, Marilyn Anderson, Marie-Isabel Aguilar   +3 more
doaj   +1 more source

Enhanced Sonodynamic Bacterial Elimination and Wound Healing Therapy Based on Lanthanide Ion Doped Bi2WO6 Nanosheets and Hydrogel Platform

Advanced Functional Materials, EarlyView.
Lanthanide ytterbium ions are introduced into Bi2WO6 nanosheets to boost ROS generation under US stimulation. These ytterbium‐doped Bi2WO6 nanosheets serve as efficient sonosensitizers, enabling broad‐spectrum bacterial eradication. To improve biocompatibility for in vivo sonodynamic therapy, the sonosensitizers are integrated into hydrogel matrix ...
Xinyue Lao, Qianqian Bai, Yifei Zhao, Xingyi Dai, Yuan Liu, Xiao Han, Jianhua Hao   +6 more
wiley   +1 more source

Polydopamine-Supported Lipid Bilayers

Materials, 2012
We report the formation of lipid membranes supported by a soft polymeric cushion of polydopamine. First, 20 nm thick polydopamine films were formed on mica substrates. Atomic force microscopy imaging indicated that these films were also soft with a surface roughness of 2 nm under hydrated conditions.
Jerome P. Claverie, Grégoire Leclair, Isabelle Marcotte, Souryvanh Nirasay, Antonella Badia   +4 more
openaire   +2 more sources

General model of phospholipid bilayers in fluid phase within the single chain mean field theory

, 2014
Coarse-grained model for saturated (DCPC, DLPC, DMPC, DPPC, DSPC) and unsaturated (POPC, DOPC) phospholipids is introduced within the Single Chain Mean Field theory.
Baulin, Vladimir A., Guo, Yachong, Pogodin, Sergey   +2 more
core   +1 more source