Results 81 to 90 of about 1,320,816 (375)
Pore-size distribution in a biomembrane model [PDF]
It is shown that spontaneous formation of pores occurs in a recently proposed exactly solvable model for a two-dimensional lipid bilayer.
Wiegel, F.W.
core +3 more sources
Supported Lipid Bilayer Assembly on PEDOT:PSS Films and Transistors
Lipid bilayers are widely employed as a model system to investigate interactions between cells and their environment. Supported lipid bilayers (SLB) with integrated transmembrane proteins are emerging as a preferred platform for sensing applications ...
Yi Zhang+6 more
semanticscholar +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Membrane-Accelerated Amyloid-β Aggregation and Formation of Cross-β Sheets
Amyloid- β aggregates play a causative role in Alzheimer’s disease. These aggregates are a product of the physical environment provided by the basic neuronal membrane, composed of a lipid bilayer.
Adree Khondker+2 more
doaj +1 more source
Functional biointerfaces hold broad significance for designing cell-responsive medical implants and sensor devices. Solid-supported phospholipid bilayers are a promising class of biological materials to build bioinspired thin-film coatings, as they can ...
Sigalit Meker+7 more
doaj +1 more source
The interaction of amyloid A beta(1-40) with lipid bilayers and ganglioside as studied by P-31 solid-state NMR [PDF]
Amyloid P-peptide (A beta) is a major component of plaques in Alzheimer's disease, and formation of senile plaques has been suggested to originate fro m regions of neuronal membrane rich in gangliosides. We analyzed the mode of interaction of A beta with
Asakura, T.+4 more
core +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Liposomal lipid nanoparticles for extrahepatic delivery of mRNA
Long-circulating, transfection-competent lipid nanoparticle (LNP)-mRNA delivery systems are critical for achieving efficient transfection in extrahepatic tissues.
Miffy Hok Yan Cheng+16 more
doaj +1 more source
A comparative study of the lipid bilayer phase status and structure of the outer membrane of free-living Bradyrhizobium strain 359a (Nod+Fix+) and 400 (Nod+FixL) or Rhizobium leguminosarum 97 (Nod+Fix+, effective) and 87 (Nod+FixL, ineffective) has been ...
Natalia N. Kudryavtseva+3 more
doaj +1 more source
Microrheology of Freestanding Lipid Bilayers [PDF]
The macroscopic material properties of cellular membranes, determined by the composition and interactions of their constituent lipids, are important factors in the structure and function of all living cells. Fluidity is a key material property of membranes, yet the underlying lipid bilayer viscosity and other rheological parameters remain poorly ...
Miranda J. Bradley+2 more
openaire +2 more sources