Results 81 to 90 of about 1,227,492 (388)

DNA-nanostructure-templated assembly of planar and curved lipid-bilayer membranes

open access: yesFrontiers in Chemistry, 2023
Lipid-bilayer nanodiscs and liposomes have been developed to stabilize membrane proteins in order to study their structures and functions. Nanodiscs are detergent-free, water-soluble, and size-controlled planar phospholipid-bilayer platforms.
Mostafa A. Elbahnasawy, Mahmoud L. Nasr
doaj   +1 more source

FLUCTUATIONS IN LIPID BILAYERS: ARE THEY UNDERSTOOD? [PDF]

open access: yesBiophysical Reviews and Letters, 2013
We review recent computer simulation studies of undulating lipid bilayers. Theoretical interpretations of such fluctuating membranes are most commonly based on generalized Helfrich-type elastic models, with additional contributions of local "protrusions" and/or density fluctuations. Such models provide an excellent basis for describing the fluctuations
openaire   +3 more sources

Monolayer curvature stabilizes nanoscale raft domains in mixed lipid bilayers [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
According to the lipid raft hypothesis, biological lipid membranes are laterally heterogeneous and filled with nanoscale ordered “raft” domains, which are believed to play an important role for the organization of proteins in membranes.
Sebastian Meinhardt, R. Vink, F. Schmid
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Simulation studies of stratum corneum lipid mixtures [PDF]

open access: yes, 2009
We present atomistic molecular dynamics results for fully hydrated bilayers composed of ceramide NS-24:0, free fatty acid 24:0 and cholesterol, to address the effect of the different components in the stratum corneum (the outermost layer of skin) lipid matrix on its structural properties.
arxiv   +1 more source

Bilayer-thickness-mediated interactions between integral membrane proteins [PDF]

open access: yesPhys. Rev. E 93, 042410 (2016), 2016
Hydrophobic thickness mismatch between integral membrane proteins and the surrounding lipid bilayer can produce lipid bilayer thickness deformations. Experiment and theory have shown that protein-induced lipid bilayer thickness deformations can yield energetically favorable bilayer-mediated interactions between integral membrane proteins, and large ...
arxiv   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Confined Multilamellae Prefer Cylindrical Morphology [PDF]

open access: yes, 2005
By evaporating a drop of lipid dispersion we generate the myelin morphology often seen in dissolving surfactant powders. We explain these puzzling nonequilibrium structures using a geometric argument: The bilayer repeat spacing increases and thus the ...
Huang, Jung-Ren   +2 more
core   +1 more source

Protein-Lipid Interaction of Cytolytic Toxin Cyt2Aa2 on Model Lipid Bilayers of Erythrocyte Cell Membrane

open access: yesToxins, 2020
Cytolytic toxin (Cyt) is a toxin among Bacillus thuringiensis insecticidal proteins. Cyt toxin directly interacts with membrane lipids for cytolytic action. However, low hemolytic activity is desired to avoid non-specific effects in mammals. In this work,
Sudarat Tharad   +2 more
doaj   +1 more source

Characterization of the Prokaryotic Sodium Channel NavSp Pore with a Microfluidic Bilayer Platform. [PDF]

open access: yesPLoS ONE, 2015
This paper describes the use of a newly-developed micro-chip bilayer platform to examine the electrophysiological properties of the prokaryotic voltage-gated sodium channel pore (Na(v)Sp) from Silicibacter pomeroyi.
Shimul Chandra Saha   +5 more
doaj   +1 more source

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