Results 161 to 170 of about 1,084,218 (302)

Detergents alter the stability and lipid binding properties of the CD1d immunoreceptor. [PDF]

Protein Sci
Miles UZ, Finn MG, McShan AC.
europepmc   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

Conformations and sequence determinants in the lipid binding of an adhesive peptide derived from Vibrio cholerae biofilms. [PDF]

PLoS Pathog
Huang X, Prasad R, Saluja S, Yang Y, Yan Q, Shuster SO, Karatekin E, Olson R, Lin C, Davis CM, Jiang X, Zhou HX, Yan J.   +12 more
europepmc   +1 more source

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

In vitro methods for measuring lipid binding, transfer and competitive displacement reactions by peripheral membrane proteins. [PDF]

Methods Enzymol
Bankaitis VA, Yu X, Chen XR, Lönnfors M, Igumenova TI.   +4 more
europepmc   +1 more source

Self‐Assembled Nanoclay Gel With Spheroid MSC‐Derived Exosome Mimetics to Integrate Demineralized Bone Matrix and Noggin‐Targeting miRNA for Synergistic Osteogenesis

Advanced Functional Materials, EarlyView.
We report a versatile nanoclay gel carrier platform that enhances the osteogenic efficacy of demineralized bone matrix (DBM) by integrating nanoclay‐based self‐assembly with cell‐derived exosome mimetics loaded with noggin‐targeting miR‐200c. This design amplifies BMP signaling, thereby promoting DBM‐mediated osteogenesis and offering a promising ...
Changlu Xu, Zhi Li, Minjee Kang, Ruoyu Sheng, Bing Han, Yiqing Chen, Tara Aghaloo, Min Lee   +7 more
wiley   +1 more source

Identifying and Characterizing Lipid-Binding Cavities in Lipid Transfer Proteins With CG-MD Simulations. [PDF]

Bio Protoc
Álvarez D, Vanni S, Srinivasan S.
europepmc   +1 more source

Potential effects of brain lipid binding protein in the pathogenesis of amyotrophic lateral sclerosis. [PDF]

Sci Prog, 2023
Zhou Q, Kang Q, Chen W, Xu R.
europepmc   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

A pathogenic mutation in α-SNAP impairs membrane lipid binding by concealing a critical hydrophobic loop. [PDF]

Commun Biol
Méndez-Ruette M, Bedoya M, Hinrichsen B, Henzi R, Muñoz-Gutiérrez C, Parga C, Muñoz C, Márquez G, Muñoz RI, Sandoval S, Ross BH, Vivar JP, Mardones GA, Brauchi S, Wyneken Ú, Michaut MA, González W, Bátiz LF.   +17 more
europepmc   +1 more source