ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai +13 more
wiley +1 more source
Lipophilic mono-guanidines <i>versus</i> mono-(thio)ureas: anion transport, lipid binding, and antibacterial activity. [PDF]
De Silva Weerakonda Arachchige RD +3 more
europepmc +1 more source
microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan +4 more
wiley +1 more source
Detergents alter the stability and lipid binding properties of the CD1d immunoreceptor. [PDF]
Miles UZ, Finn MG, McShan AC.
europepmc +1 more source
Laser‐Induced Graphene from Waste Almond Shells
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
A lipid-binding protein that boosts daytime wake is mainly located at the body surface and blocks light-induced lipid peroxidation in the brain. [PDF]
Love CR, Edery I.
europepmc +1 more source
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Conformations and sequence determinants in the lipid binding of an adhesive peptide derived from Vibrio cholerae biofilms. [PDF]
Huang X +12 more
europepmc +1 more source
Binding of Bilirubin with Lipid
Mohammad G. Mustafa, Tsoo E. King
openaire +1 more source
Lipid Content in the Sea Urchin Embryos under Nickel Stress
Nickel is a heavy metal toxic for living organisms even at low concentrations. Sea urchin embryos represent a good model system for testing the effects of physical and chemical stress, like heavy metals, on development and cell viability.
황진익 +3 more
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