Results 251 to 260 of about 2,675,614 (299)

Lipid Binding of SH2 Domains

2023
The Src homology 2 (SH2) domain is a modular protein interaction domain that specifically recognizes the phosphotyrosine (pY) motif of a target molecule. We recently reported that a large majority of human SH2 domains tightly bind membrane lipids, and many show high lipid specificity.
Wonhwa, Cho, Kyli, Berkley, Ashutosh, Sharma   +2 more
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The lipid-binding SEC14 domain

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2007
Protein-lipid interactions are important for protein targeting, signal transduction, lipid transport, lipid biosynthesis, lipid metabolism, and the maintenance of cellular compartments and membranes. Specific lipid-binding protein domains, such as PH, FYVE, PX, PHD, C2 and SEC14 homology domains, mediate interactions between proteins and specific ...
Kan, Saito, Lutz, Tautz, Tomas, Mustelin
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Binding of glucagon to lipid bilayers

Biochemistry and Cell Biology, 1990
At physiological pH and temperature, glucagon binds to liposomes composed of egg phosphatidylcholine and cholesterol (2:1 mol/mol) in a highly specific manner. The chemical reactivities of the functional groups were determined over the concentration range of 1.0 × 10−6 – 3.0 × 10−8 M by the method of competitive labelling with 1-fluoro-2,4 ...
R P, Oomen, H, Kaplan
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The binding of micellar lipids to chitosan

Lipids, 1983
AbstractThe lipid binding capacity of chitosan (partially deacetylated chitin) was determinined with respect to micellar solutions of bile salts, dodecyl sulfate, natural ox bile and an artificial mixed microemulsion. The stoichiometry was determined following the separation of the solid phase by filtration or centrifugation. The major variables in the
J L, Nauss, J L, Thompson, J, Nagyvary
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Identification of Lipid-Binding Effectors

2011
In recent years, the functional roles of effectors from a wide variety of fungal and oomycete pathogens have begun to emerge. As a product of this work, the importance of effector-lipid interactions has been made apparent. Phospholipids are not only important signaling molecules, but they also play important roles in the trafficking of endosomes and ...
Shiv D, Kale, Brett M, Tyler
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Assembly and characterization of lipid–lipid binding protein particles

Journal of Biotechnology, 2011
Lipid-protein complexes, lipoplexes, are currently of great interest because of their immunogenic, gene free, and low cost properties. For their applications as potential vaccines, it is critical to display a target protein on the surface of lipoplex particles to allow external interactions to take place. However, how to effectively assemble lipoplexes
Wei, Huang, Chenming, Zhang
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Lipid Mobility and Molecular Binding in Fluid Lipid Membranes

Journal of the American Chemical Society, 2005
The lateral mobility of dilute concentrations of fluorescently labeled lipids doped into supported membranes is found to change upon receptor ligand binding at the membrane surface, even when the lipid is not directly involved in the binding event.
Victoria, Yamazaki, Oksana, Sirenko, Robert J, Schafer, Jay T, Groves   +3 more
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The Binding of Calcium at Lipid-Water Interfaces

European Journal of Biochemistry, 1967
Measurements have been made of the binding of radioactive calcium to unimolecular films of purified lipids equivalent to those found in cell membranes.The adsorption of 45Ca on pure phospholipid films is largely independent of the chemical nature of the phospholipid.
H, Hauser, R M, Dawson
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Binding of Lipids on Lipid Transfer Proteins

1997
LTPs transfer phospholipids between membranes “in vitro” (1). Plant LTPs are still in search of an “in vivo” role. These proteins share in common structural and functional properties (1). NMR and X-ray crystallography have been carried out on plant LTPs.
F. Guerbette, A. Jolliot, J.-C. Kader, M. Grosbois   +3 more
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Titration calorimetry as a binding assay for lipid-binding proteins

Molecular and Cellular Biochemistry, 1993
Titration calorimetry has been evaluated as a method for obtaining binding constants and thermodynamic parameters for the cytosolic fatty acid- and lipid-binding proteins. An important feature of this method was its ability to accurately determine binding constants in a non-perturbing manner.
K R, Miller, D P, Cistola
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