Results 261 to 270 of about 2,675,614 (299)

Lipid Binding Domains

Science's STKE, 2000
Signals can be regulated by many flexible strategies, including blocking protein catalytic activity, reducing product accumulation, or sequestrating proteins from their site of action. Several protein binding domains that regulate the interaction of proteins with each other have been identified.
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Lipid Binding of Membrane Proteins

1972
There is increasing evidence at present time that about half of the proteins of various biomembrane-types are bound to the lipids within the membrane by predominantly hydrophobic interaction (1). But almost nothing is Known about what sequences or regions of the membrane polypeptides do bind to the acyl chains of the lipids.
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Amyloid A: amphipathic helixes and lipid binding

Biochemistry, 1976
Polypeptide segments, composed of alpha helixes with specific surface topography termed amphipathic helixes, have been proposed as the basic lipid-associating domains of apolipoproteins from the plasma lipoproteins. A computer search for proteins having sequences that could form amphipathic helixes indicated that amyloid A, a pathologically occurring ...
J P, Segrest, H J, Pownall, R L, Jackson, G G, Glenner, P S, Pollock   +4 more
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The mechanism of lipid-binding by plasma lipoproteins

Molecular and Cellular Biochemistry, 1975
In this article, we review the current state of knowledge about the structure of human plasma high density lipoproteins. Recent advances in this field, including amino acid sequencing and lipid-binding studies, suggest that the plasma lipoproteins have specific sites with special structural features that account for their ability to bind and transport ...
R L, Jackson, J D, Morrisett, A M, Gotto, J P, Segrest   +3 more
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Diphenylhydantoin binding to brain lipids and phospholipids

Biochemical Pharmacology, 1976
Abstract Partition coefficients for diphenylhydantoin (DPH) were determined using four organic solvents and a 0.1 M phosphate buffer. Values ranged from 25.5 for chloroform to 0.02 for hexane. When chloroform-methanol-soluble brain lipids were added, there was a marked enhancement of DPH entry into hexane; 2 mg lipid resulted in an almost equal ...
M A, Goldberg, T, Todoroff
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Lipid binding capacity of spider hemocyanin

Journal of Experimental Zoology, 1999
The spider hemocyanin capacity to bind different lipid classes was evaluated by measuring some binding kinetic parameters. A very high lipoprotein (VHDL) which contains hemocyanin, was isolated from Polybetes pythagoricus hemolymph plasma and delipidated.
M, Cunningham, C, Gómez, R, Pollero
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d-amphetamine binding to brain lipid

Neurochemical Research, 1978
The interaction of d-amphetamine with several brain tissue components has been investigated. A brain lipid extract and a number of individual phospholipids were found to bind d-amphetamine when measured by means of a hexane-buffer partition coefficient technique.
M A, Goldberg, T, Todoroff
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Lipid Affinity Beads: From Identifying New Lipid Binding Proteins to Assessing Their Binding Properties

2013
Lipid affinity beads can be used to identify novel proteins with lipid binding capacity or to determine binding prerequisites of known lipid-binding proteins. Here we describe several applications for which this tool can be used and which considerations have to be taken into account.
McLoughlin, F., Testerink, C.
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Binding of myosin I to membrane lipids

Nature, 1989
The single-headed myosins called myosin-I were first isolated from the protozoan Acanthamoeba and subsequently identified in other cells. We previously reported evidence that myosin-I is responsible for the movement of membranes, extracted from Acanthamoeba, along actin filaments in vitro. Here we show for the first time that myosin-I can bind directly
R J, Adams, T D, Pollard
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Probing the Binding of Cationic Lipids with Dendrimers

Biomacromolecules, 2012
Polycationic polymers are used extensively in biology to disrupt cell membranes and thus enhance the transport of materials into the cell. We report the bindings of several lipids cholesterol (Chol), 1,2-dioleoyl-3-trimethylammonium-propane(DOTAP), dioctadecyldimethylammoniumbromide (DDAB), and dioleoylphosphatidylethanolamine (DOPE) to dendrimers of ...
J S, Mandeville, P, Bourassa, H A, Tajmir-Riahi   +2 more
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