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Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates
Angewandte Chemie, EarlyView.An alkyne‐tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the Kennedy pathway, allowing CuAAC‐based visualization of PE and affinity capture of PE‐conjugated LC3, ubiquitin, and GPI‐anchored proteins.
Yuan‐Ting Cho +5 more
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Chloroplast Lipids and Their Biosynthesis
Annual Review of Plant Biology, 2019Chloroplasts contain high amounts of monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) and low levels of the anionic lipids sulfoquinovosyldiacylglycerol (SQDG), phosphatidylglycerol (PG), and glucuronosyldiacylglycerol (GlcADG).
Georg, Hölzl, Peter, Dörmann
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Vyziva lidu, 2004
During the late 1930s, Barker isolated an anaerobic bacterium which he called Clostridium kluyveri. This organism is able to grow on a mixture of acetate and ethanol and produces n-butyrate and n-caproate. From this organism, Barker and Stadtman obtained cell-free extracts which could carry the reactions leading to the C4 and C6 acids.
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During the late 1930s, Barker isolated an anaerobic bacterium which he called Clostridium kluyveri. This organism is able to grow on a mixture of acetate and ethanol and produces n-butyrate and n-caproate. From this organism, Barker and Stadtman obtained cell-free extracts which could carry the reactions leading to the C4 and C6 acids.
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Biosynthesis of Membrane Lipids
EcoSal Plus, 2008The pathways in Escherichia coli and (largely by analogy) S. enterica remain the paradigm of bacterial lipid synthetic pathways, although recently considerable diversity among bacteria in the specific areas of lipid synthesis has been demonstrated.
John E, Cronan, Charles O, Rock
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Biosynthesis and biotransformation of ether lipids
Lipids, 1987AbstractSome naturally occurring as well as synthetic ether lipids are biologically active. In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis. The biotrans‐formation of natural or “unnatural” ether lipids in microorganisms,
H K, Mangold, N, Weber
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Lipid biosynthesis by human endometrium
American Journal of Obstetrics and Gynecology, 1966Abstract Previous investigators have demonstrated that lipid biosynthesis by animal endometrium is subject to the control of hormones. Chemical analyses and histochemical studies are available, but there are no previous studies of actual lipid biosynthesis by human endometrium.
J A, Merrill, N T, Werthessen
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Inhibitors of ether lipid biosynthesis
Biochemical and Biophysical Research Communications, 1981Abstract During biosynthesis of ether lipids, fatty alcohols may add covalently to ene-diol esters that would result from isomerization of acyl-dihydroxyacetone phosphate. Palmitoylation of 1,2,3-trihydroxyeicosane 1-phosphate, obtained by epoxidation of the product obtained by vinyllithiation of octadecanal, yields stable analogs of the high-energy ...
S, Hixson, R, Wolfenden
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Lipid Biosynthesis and Degradation
2021Lipids form an integral part of a microbial cell. Lipid composition varies among different groups of bacteria and archaea and is also used as a taxonomic criterion for identification. Fatty acids are the basic components of lipids. Hence, lipid biosynthesis initiates with fatty acid biosynthesis followed by their transfer to glycerol backbone.
Rani Gupta, Namita Gupta
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Epidermal lipid biosynthesis in acne
British Journal of Dermatology, 1980Lipid biosynthesis from glucose was increased in severe acne both in dermis and in epidermis which included the top portions of the pilosebaceous follicles. Both tissues retained their characteristic lipid labelling pattern. The magnitude of the increase in dermis and epidermis was similar, suggesting that epidermis may be subject to the same ...
S, Shuster +3 more
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The Biosynthesis and Applications of Protein Lipidation
Chemical ReviewsProtein lipidation dramatically affects protein structure, localization, and trafficking via remodeling protein-membrane and protein-protein interactions through hydrophobic lipid moieties. Understanding the biosynthesis of lipidated proteins, whether natural ones or mimetics, is crucial for reconstructing, validating, and studying the molecular ...
Wenlong Ding +6 more
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