Results 221 to 230 of about 227,142 (264)

Studies on the biosynthesis of lipids in the baboon. biosynthesis and transport of cholesterol

Clinica Chimica Acta, 1965
Abstract The transport of exogenous and/or endogenous cholesterolin the baboon has been studied using [1-14C] acetate, [2-14C] mevalonic acid and 3H- and 14C-labeled cholesterol. The peak specific activity of the serum free cholesterol derived from [2-14C] mevalonic acid was reached in 4–10 h and the free and esterified forms equilibrated by 72 h ...
D, KRITCHEVSKY, N T, WERTHESSEN, I L, SHAPIRO   +2 more
openaire   +2 more sources

Lipid A Biosynthesis

1992
Lipid A, a constituent of the outer membrane of gram-negative bacteria, is a structurally unique molecule that does not exist in animal cells. The lipid A of most gram-negative bacteria is structurally similar, with analogous biosynthetic steps. These facts, combined with the fact that lipid A is required for the survival of most, if not all gram ...
openaire   +1 more source

Lipid biosynthesis in oleaginous yeasts

1989
With the increasing demands for fats and oils for edible and industrial purposes, many assessments have been made to find new possible lipid sources other than from the conventional plants and animals. Lipids from microbial origin could represent such an alternative since microorganisms can store up to 65% fat in the cells and can be harvested in a ...
G. Turcotte, N. Kosaric
openaire   +1 more source

Biosynthesis of Lipids in Tumoral Cells

1977
Tumor cells are known to differ from normal cells in lipid metabolism. Many laboratories have focused their interest to make some insight on the relationship between malignancy and alteration in lipid metabolism, since lipids are recognized in their importance as components of membrane structures.
M E, De Tomás, O, Mercuri
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Biosynthesis, transport, and modification of lipid A

Biochemistry and Cell Biology, 2004
Lipopolysaccharide (LPS) is the major surface molecule of Gram-negative bacteria and consists of three distinct structural domains: O-antigen, core, and lipid A. The lipid A (endotoxin) domain of LPS is a unique, glucosamine-based phospholipid that serves as the hydrophobic anchor of LPS and is the bioactive component of the molecule that is ...
openaire   +3 more sources

Lipidation Engineering in Daptomycin Biosynthesis

Journal of the American Chemical Society
Lipopeptides are an important family of natural products, some of which are clinically used as antibiotics to treat multidrug-resistant pathogens. Although the lipid moieties play a crucial role in balancing antibacterial activity and hemolytic toxicity, modifying the lipid moieties has been challenging due to the complexity of the lipidation process ...
Chang-Hun Ji, Sehong Park, Kunwoo Lee, Hyun-Woo Je, Hahk-Soo Kang   +4 more
openaire   +2 more sources

Genetics and Biosynthesis of Lipid A

2011
The defining feature of Gram-negative bacteria is the presence of an outer membrane, which comprises the outermost surface of the cell envelope and is, therefore, in constant contact with the surrounding environment. The Gram-negative outer membrane is unique as compared to most biological membranes in that it is an asymmetric bilayer composed of a ...
Christopher M. Stead, Aaron C. Pride, M. Stephen Trent   +2 more
openaire   +1 more source

Analysis of Lipid Biosynthesis and Location

2009
A procedure for metabolic labeling of all cellular lipids starting with a culture of mycobacteria is described in this chapter using either a pulse-chase or a simple labeling experimental design. Three fractions are produced for subsequent lipid analysis: (1) the culture filtrate; (2) a readily released surface lipid fraction; and (3) the killed ...
openaire   +2 more sources

Lipid Biosynthesis

2021
Caroline Bowsher, Alyson Tobin
openaire   +1 more source

Regulatory mechanisms of lipid biosynthesis in microalgae

Biological Reviews, 2021
Hui Chen, Qiang Wang
exaly