Results 111 to 120 of about 814,728 (297)

Further evidence that the narrow 1H magnetic resonance signals from malignant cells do not arise from intracellular lipid droplets

open access: yes, 1989
1H magnetic resonance (MR) spectroscopy of intact viable malignant cells yields high resolution spectra from lipid. In previous studies we have provided evidence that these signals are generated by neutral lipid located in the plasma membrane in unique ...
Dyne, Marlen   +4 more
core   +1 more source

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang   +4 more
wiley   +1 more source

Lipid droplet detection in histopathological images using reinforcement learning

open access: yesBiotechnology & Biotechnological Equipment
The identification and analysis of lipid droplets in pathological images are pivotal owing to the variations in their size, shading and shape. The development of an artificial intelligence-based automatic detection method can facilitate the analysis of ...
Yoshitomi Harada   +2 more
doaj   +1 more source

The proteomics of lipid droplets: structure, dynamics, and functions of the organelle conserved from bacteria to humans

open access: yesJournal of Lipid Research, 2012
Lipid droplets are cellular organelles that consists of a neutral lipid core covered by a monolayer of phospholipids and many proteins. They are thought to function in the storage, transport, and metabolism of lipids, in signaling, and as a specialized ...
Li Yang   +11 more
doaj   +1 more source

Autophagy and Lipid Droplets in the Liver

open access: yesAnnual Review of Nutrition, 2015
Autophagy is a conserved quality-control pathway that degrades cytoplasmic contents in lysosomes. Autophagy degrades lipid droplets through a process termed lipophagy. Starvation and an acute lipid stimulus increase autophagic sequestration of lipid droplets and their degradation in lysosomes. Accordingly, liver-specific deletion of the autophagy gene
Nuria, Martinez-Lopez, Rajat, Singh
openaire   +3 more sources

Laser‐Induced Graphene from Waste Almond Shells

open access: yesAdvanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova   +9 more
wiley   +1 more source

LRRK2 mediated Rab8a phosphorylation promotes lipid storage

open access: yesLipids in Health and Disease, 2018
Background Several mutations in leucine rich repeat kinase 2 (LRRK2) gene have been associated with pathogenesis of Parkinson’s disease (PD), a neurodegenerative disorder marked by resting tremors, and rigidity, leading to Postural instability.
Miao Yu   +5 more
doaj   +1 more source

Data underlying the publication: Lipid-Mediated Control of Thermally Induced Shape Transformations in Liquid Crystal Droplets

open access: yes
Data underlying Chapter 4 of the PhD thesis of Mengwei Li (Utrecht University), "Lipid-Mediated Control of Thermally Induced Shape Transformations in Liquid Crystal Droplets". Samples.
Tran, Lisa, Li, Mengwei
core   +1 more source

A molecular logic gate enables super-resolved imaging of intracellular lipid droplets [PDF]

open access: yes
Photoactivatable dyes enable single-mol. imaging in biol. Despite progress in the development of new fluorophores and labeling strategies, many cellular compartments remain difficult to image beyond the limit of diffraction in living cells.
Rivera Fuentes, Pablo   +4 more
core   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

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