Results 351 to 360 of about 1,446,619 (399)

Defective targeting of PNPLA1 to lipid droplets causes ichthyosis in ABHD5-syndromic epidermal differentiation disorder. [PDF]

J Lipid Res
Schratter M, Holubek D, Koeffler L, Züllig T, Eichmann TO, Wolinski H, Oberer M, Lass A, Radner FPW.   +8 more
europepmc   +1 more source

Functional study of Phaeodactylum tricornutum Seipin highlights specificities of lipid droplets biogenesis in diatoms. [PDF]

New Phytol
Le Moigne D, Carletti M, Amari C, Bonnarde R, Richard F, Albrieux C, Mahieu M, Arrighi M, Si-Larbi G, Jouneau PH, Gros V, Louwagie M, Roy S, Gong Y, Pan Y, Hu H, Bastien O, Jouhet J, Amato A, Maréchal E, Salvaing J.   +20 more
europepmc   +1 more source

Exploring the role of hepatic lipid droplets in mouse liver toxicity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin: sequestration, biochemical alterations and gene regulation. [PDF]

Sci Rep
Hammoudeh N, Soukkarieh C, Hanano A.
europepmc   +1 more source

GRIM MATLAB demos: core-CE derivation and lipid droplet unmixing

Samuel T. Freer
openalex   +1 more source

Exploring novel roles of lipid droplets and lipid metabolism in regulating inflammation and blood-brain barrier function in neurological diseases. [PDF]

Front Neurosci
Fu L, Luo T, Hao Z, Pan Y, Xin W, Zhang L, Lai Z, Zhang H, Liu H, Wei W.   +9 more
europepmc   +1 more source

Remodelled cholesteryl ester enriched lipid droplets fuel flavivirus morphogenesis

Banducci-Karp A, Brixton S, Shah PNM, Li M, Fisher G, Riepsaame J, Dhaliwal R, Holden KL, Drydale E, Bancroft J, Melia CE, Malavige GN, Sanyal S.   +12 more
europepmc   +1 more source

Lipid droplets and cellular lipid flux [PDF]

Nature Cell Biology
Lipid droplets are dynamic organelles that store neutral lipids, serve the metabolic needs of cells, and sequester lipids to prevent lipotoxicity and membrane damage. Here we review the current understanding of the mechanisms of lipid droplet biogenesis and turnover, the transfer of lipids and metabolites at membrane contact sites, and the role of ...
Alyssa J. Mathiowetz, James A. Olzmann
semanticscholar   +3 more sources

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Polarity-Sensitive Ratiometric Fluorescence Probe for Monitoring Lipid Droplets/Nucleus Change During Ferroptosis.

Angewandte Chemie, 2021
Ferroptosis regulates cell death through reactive oxygen species associated lipid peroxide accumulation, which is expected to affect the structure and polarity of lipid droplets (LDs), but with no clear evidence. Herein, we report the first example of LD
Kang‐Nan Wang, Liu‐Yi Liu, Duo Mao, Shidang Xu, Cai-Ping Tan, Qian Cao, Z. Mao, Bin Liu   +7 more
semanticscholar   +1 more source

Adipocyte‐Derived Anticancer Lipid Droplets

Advanced Materials, 2021
AbstractEngineering of efficient and safe materials remains a challenge for cancer therapy. Here, the lipid droplet, an organelle in adipocytes, is demonstrated to be a controllable and biocompatible vehicle to deliver anticancer drugs. It is validated that isolated lipid droplets maintain their key physiological functions to interact with other ...
Tingxizi Liang, Di Wen, Guojun Chen, Amanda Chan, Zhaowei Chen, Hongjun Li, Zejun Wang, Xiao Han, Liping Jiang, Jun‐Jie Zhu, Zhen Gu   +10 more
semanticscholar   +3 more sources

Triglyceride containing lipid droplets and lipid droplet-associated proteins

Current Opinion in Lipidology, 2008
Cytosolic lipid droplets are now recognized as dynamic organelles. This review summarizes our current understanding of the mechanisms involved in the formation of lipid droplets, the importance of lipid droplet-associated proteins and the link between lipid droplet accumulation and development of insulin resistance.Lipid droplets are formed as ...
Sven-Olof, Olofsson, Pontus, Boström, Linda, Andersson, Mikael, Rutberg, Malin, Levin, Jeanna, Perman, Jan, Borén   +6 more
openaire   +2 more sources