Results 11 to 20 of about 4,822 (217)
Lipid II as a target for antibiotics [PDF]
Nature Reviews Drug Discovery, 2006 Lipid II is a membrane-anchored cell-wall precursor that is essential for bacterial cell-wall biosynthesis. The effectiveness of targeting Lipid II as an antibacterial strategy is highlighted by the fact that it is the target for at least four different classes of antibiotic, including the clinically important glycopeptide antibiotic vancomycin ...
Breukink, E.J., de Kruijff, B.
openaire +6 more sources
PLoS ONE, 2016 BackgroundApolipoprotein A-II (ApoA-II) is down regulated in the sera of pancreatic ductal adenocarcinoma (PDAC) patients, which may be due to increase utilization of high density lipoprotein (HDL) lipid by pancreatic cancer tissue.
Sohel M Julovi +9 more
doaj +1 more source
Journal of Lipid Research, 1999 We examined the effect of lipid-free apolipoprotein A-I (apoA-I) and apoA-II on the structure of reconstituted high density lipoproteins (rHDL) and on their reactivity as substrates for lecithin:cholesterol acyltransferase (LCAT). First, homogeneous rHDL
Diane M. Durbin, Ana Jonas
doaj +1 more source
Asian Journal of Medical Sciences, 2018 Background: Type II Diabetes Mellitus (Type II DM) is a metabolic disorder characterized by glucotoxicity and lipotoxicity. Marker of glycemic control are HbA1c, fasting blood glucose and postprandial blood glucose.
Vijay Kumar Sharma +8 more
doaj +1 more source
Bio-Protocol, 2018 Peptidoglycan encases the bacterial cytoplasmic membrane to protect the cell from lysis due to the turgor. The final steps of peptidoglycan synthesis require a membrane-anchored substrate called lipid II, in which the peptidoglycan subunit is linked to ...
Manuel Pazos +2 more
doaj +1 more source
Frontiers in Microbiology, 2020 Planktonic archaea include predominantly Marine Group I Thaumarchaeota (MG I) and Marine Group II Euryarchaeota (MG II), which play important roles in the oceanic carbon cycle. MG I produce specific lipids called isoprenoid glycerol dibiphytanyl glycerol
Cenling Ma +5 more
doaj +1 more source
AmiD Is a Novel Peptidoglycan Amidase in Wolbachia Endosymbionts of Drosophila melanogaster
Frontiers in Cellular and Infection Microbiology, 2017 Wolbachia endobacteria are obligate intracellular bacteria with a highly reduced genome infecting many arthropod and filarial species, in which they manipulate arthropod reproduction to increase their transmission and are essential for nematode ...
Miriam Wilmes +10 more
doaj +1 more source
Quality control of photosystem II: lipid peroxidation accelerates photoinhibition under excessive illumination. [PDF]
PLoS ONE, 2012 Environmental stresses lower the efficiency of photosynthesis and sometimes cause irreversible damage to plant functions. When spinach thylakoids and Photosystem II membranes were illuminated with excessive visible light (100-1,000 µmol photons m(-1) s ...
Tiffanie Chan +17 more
doaj +1 more source
Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly
Drug Design, Development and Therapy, 2020 Jay Chauhan,1 Wenbo Yu,2 Steven Cardinale,3 Timothy J Opperman,3 Alexander D MacKerell Jr,2,4 Steven Fletcher,1 Erik PH de Leeuw1 1Institute of Human Virology & Department of Biochemistry and Molecular Biology of the University of Maryland Baltimore ...
Chauhan J +6 more
doaj
Phospholipids mediated conversion of HDLs generates specific apoA-II pre-β mobility particles
Journal of Lipid Research, 2009 Apolipoproteins (apo)A-I and A-II are major proteins of human HDL. The cycling of apoA-I between lipid-poor and lipid-rich forms of HDL plays a key role in the transport of cholesterol by these particles.
Małgorzata Wróblewska +3 more
doaj +1 more source