Insights in the Antimicrobial Potential of the Natural Nisin Variant Nisin H [PDF]
Frontiers in Microbiology, 2020 Lantibiotics are a growing class of antimicrobial peptides, which possess antimicrobial activity against mainly Gram-positive bacteria including the highly resistant strains such as methicillin-resistant Staphylococcus aureus or vancomycin-resistant ...
Jens Reiners +11 more
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Nisin-like biosynthetic gene clusters are widely distributed across microbiomes [PDF]
mBioBacteriocins are antimicrobial peptides/proteins that can have narrow or broad inhibitory spectra and remarkable potency against clinically relevant pathogens.
David Hourigan +6 more
doaj +2 more sources
Sensitivity of Paucilactobacillus wasatchensis strains to nisin [PDF]
JDS CommunicationsPaucilactobacillus wasatchensis is a nonstarter lactic acid bacterium that has been isolated throughout the United States and is associated with late blowing gas defect (LBD), a continuing problem in the cheese industry, which results in downgraded ...
Kate Sorensen +2 more
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Nisin and nisin-loaded nanoparticles: a cytotoxicity investigation
Drug Development and Industrial Pharmacy, 2022 Nisin is an antibacterial peptide with anticancer properties, but the main drawback is its rapid enzymatic degradation and limited permeation across the cell membrane. This research aims to overcome these drawbacks by developing nisin-loaded nanoparticles (NPN) with improved cytotoxic effects.
Tanweer Haider +5 more
openaire +2 more sources
Efficacy of microencapsulated nisin with sodium alginate and chitosan on biofilm formation in Listeria monocytogenes [PDF]
Bihdāsht-i Mavādd-i Ghaz̠āyī, 2022 Listeria monocytogenes is a foodborne pathogen the cause of listeriosis that has long-term survival due to biofilm formation. This study aimed to investigate the efficacy of nisin 102 IU/ml, encapsulated nisin with chitosan and sodium alginate on biofilm
S. Babakhani +3 more
doaj +1 more source
Bioengineering nisin to overcome the nisin resistance protein [PDF]
Molecular Microbiology, 2019 SummaryThe emergence and dissemination of antibiotic resistant bacteria is a major medical challenge. Lantibiotics are highly modified bacterially produced antimicrobial peptides that have attracted considerable interest as alternatives or adjuncts to existing antibiotics.
Des Field +6 more
openaire +4 more sources
The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisC. [PDF]
PLoS ONE, 2013 Precursor nisin is a model posttranslationally modified precursor lantibiotic that can be structurally divided into a leader peptide sequence and a modifiable core peptide part.
Rustem Khusainov, Oscar P Kuipers
doaj +1 more source
Nisin E Is a Novel Nisin Variant Produced by Multiple Streptococcus equinus Strains
Microorganisms, 2023 Nisin A, the prototypical lantibiotic, is an antimicrobial peptide currently utilised as a food preservative, with potential for therapeutic applications.
Ivan Sugrue +6 more
doaj +1 more source
Nisin ZP, a Bacteriocin and Food Preservative, Inhibits Head and Neck Cancer Tumorigenesis and Prolongs Survival. [PDF]
PLoS ONE, 2015 The use of small antimicrobial peptides or bacteriocins, like nisin, to treat cancer is a new approach that holds great promise. Nisin exemplifies this new approach because it has been used safely in humans for many years as a food preservative, and ...
Pachiyappan Kamarajan +8 more
doaj +1 more source
Gene-Trait Matching and Prevalence of Nisin Tolerance Systems in Lactococus lactis
Frontiers in Bioengineering and Biotechnology, 2021 Lactococcus lactis cheese starter cultures typically contain a mix of many strains and may include variants that produce and/or tolerate the antimicrobial bacteriocin nisin. Nisin is well-established as an effective agent against several undesirable Gram-
Lieke A. van Gijtenbeek +9 more
doaj +1 more source