Results 11 to 20 of about 25,759 (221)

Bioengineering nisin to overcome the nisin resistance protein [PDF]

Molecular Microbiology, 2019
SummaryThe emergence and dissemination of antibiotic resistant bacteria is a major medical challenge. Lantibiotics are highly modified bacterially produced antimicrobial peptides that have attracted considerable interest as alternatives or adjuncts to existing antibiotics.
Des Field, Tony Blake, Harsh Mathur, Paula M. O' Connor, Paul D. Cotter, R. Paul Ross, Colin Hill   +6 more
openaire   +4 more sources

The presence of modifiable residues in the core peptide part of precursor nisin is not crucial for precursor nisin interactions with NisB- and NisC. [PDF]

PLoS ONE, 2013
Precursor nisin is a model posttranslationally modified precursor lantibiotic that can be structurally divided into a leader peptide sequence and a modifiable core peptide part.
Rustem Khusainov, Oscar P Kuipers
doaj   +1 more source

Nisin E Is a Novel Nisin Variant Produced by Multiple Streptococcus equinus Strains

Microorganisms, 2023
Nisin A, the prototypical lantibiotic, is an antimicrobial peptide currently utilised as a food preservative, with potential for therapeutic applications.
Ivan Sugrue, Daragh Hill, Paula M. O’Connor, Li Day, Catherine Stanton, Colin Hill, R. Paul Ross   +6 more
doaj   +1 more source

Nisin ZP, a Bacteriocin and Food Preservative, Inhibits Head and Neck Cancer Tumorigenesis and Prolongs Survival. [PDF]

PLoS ONE, 2015
The use of small antimicrobial peptides or bacteriocins, like nisin, to treat cancer is a new approach that holds great promise. Nisin exemplifies this new approach because it has been used safely in humans for many years as a food preservative, and ...
Pachiyappan Kamarajan, Takayuki Hayami, Bibiana Matte, Yang Liu, Theodora Danciu, Ayyalusamy Ramamoorthy, Francis Worden, Sunil Kapila, Yvonne Kapila   +8 more
doaj   +1 more source

Conjugation of Synthetic Polyproline Moietes to Lipid II Binding Fragments of Nisin Yields Active and Stable Antimicrobials

Frontiers in Microbiology, 2020
Coupling functional moieties to lantibiotics offers exciting opportunities to produce novel derivatives with desirable properties enabling new functions and applications.
Jingjing Deng, Jakob H. Viel, Vladimir Kubyshkin, Vladimir Kubyshkin, Nediljko Budisa, Nediljko Budisa, Oscar P. Kuipers   +6 more
doaj   +1 more source

Bactericidal Effect of Combination of Atmospheric Pressure Plasma and Nisin on Meat Products Inoculated with Escherichia coli O157:H7

Food Science of Animal Resources, 2023
This study was conducted to investigate the bactericidal effect of nisin (Nisin) only, atmospheric pressure plasma (APP) only, and a combination of APP and nisin (APP+Nisin) on beef jerky and sliced ham inoculated with Escherichia coli O157:H7, gram ...
Hag Ju Lee, Yeseul Heo, Hye-Jin Kim, Ki Ho Baek, Dong-Gyun Yim, Anand Kumar Sethukali, Dongbin Park, Cheorun Jo   +7 more
doaj   +1 more source

Gene-Trait Matching and Prevalence of Nisin Tolerance Systems in Lactococus lactis

Frontiers in Bioengineering and Biotechnology, 2021
Lactococcus lactis cheese starter cultures typically contain a mix of many strains and may include variants that produce and/or tolerate the antimicrobial bacteriocin nisin. Nisin is well-established as an effective agent against several undesirable Gram-
Lieke A. van Gijtenbeek, Thomas H. Eckhardt, Lucía Herrera-Domínguez, Elke Brockmann, Kristian Jensen, Asger Geppel, Kristian Fog Nielsen, Jannik Vindeloev, Ana Rute Neves, Gunnar Oregaard   +9 more
doaj   +1 more source

Pneumococcal Gene Complex Involved in Resistance to Extracellular Oxidative Stress [PDF]

, 2012
Streptococcus pneumoniae is a Gram-positive bacterium which is a member of the normal human nasopharyngeal flora but can also cause serious disease such as pneumonia, bacteremia, and meningitis. Throughout its life cycle, S.
Anne de Jong, Barbuti, Battig, Bijlsma, Bogaert, Bortoni, Braun, Brot, Bus, Carlos J. Orihuela, Cecilia A. Hinojosa, Chae, Chen, de Ruyter, Dopazo, Duane, Even, Falord, Haasum, Hendriksen, Hiller, Hirst, Holmgren, Holmgren, Hoshi, Hoskins, Ibrahim, Imlay, Imlay, J. N. Weiser, Jetta J. E. Bijlsma, Kadioglu, Kim, Kloosterman, Kloosterman, Kuipers, Lau, Liu, Liu, Liu, Marchler-Bauer, Margolis, Martner, Matthias, McAllister, Miller, Neef, Novak, Obert, Orihuela, Oscar P. Kuipers, Park, Parra-Lopez, Paterson, Pearce, Pericone, Pericone, Pericone, Pesakhov, Petit, Potter, Ramos-Montanez, Regev-Yochay, Robertson, Rosen, Schaper, Skaar, Spellerberg, Sun, Terzaghi, Tettelin, Tseng, Vahid Farshchi Andisi, Yesilkaya, Ziegelhoffer, Zweers   +75 more
core   +13 more sources

The efficacy of nisin against Listeria monocytogenes on cold-smoked salmon at natural contamination levels is concentration-dependent and varies by serotype

Frontiers in Microbiology, 2022
Cold-smoked salmon is a ready-to-eat food product capable of supporting Listeria monocytogenes growth at refrigeration temperatures. While the FDA-approved antimicrobial nisin can be used to mitigate L.
Ruixi Chen, Jordan William Skeens, Martin Wiedmann, Veronica Guariglia-Oropeza   +3 more
doaj   +1 more source

The Orientation of Nisin in Membranes [PDF]

Biochemistry, 1998
Nisin is a 34 residue long peptide belonging to the group A lantibiotics with antimicrobial activity against Gram-positive bacteria. The antimicrobial activity is based on pore formation in the cytoplasmic membrane of target organisms. The mechanism which leads to pore formation remains to be clarified.
Breukink, Eefjan, Van Kraaij, Cindy, Van Dalen, Annemieke, Demel, Rudy A., Siezen, Roland J., De Kruijff, Ben, Kuipers, Oscar P.   +6 more
openaire   +3 more sources