Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park +15 more
wiley +1 more source
The role of CYP-sEH derived lipid mediators in regulating mitochondrial biology and cellular senescence: implications for the aging heart. [PDF]
Yousef A +4 more
europepmc +1 more source
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang +6 more
wiley +1 more source
Specialized Pro-Resolving Lipid Mediators Distinctly Modulate Silver Nanoparticle-Induced Pulmonary Inflammation in Healthy and Metabolic Syndrome Mouse Models. [PDF]
Pitchai A +4 more
europepmc +1 more source
Brown Adipose Tissue Activation in Humans Increases Plasma Levels of Lipid Mediators.
Walker ME +5 more
europepmc +1 more source
Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression? [PDF]
Broos JY +7 more
europepmc +1 more source
The calcineurin-NFATc pathway modulates the lipid mediators in BAL fluid extracellular vesicles, thereby regulating microvascular endothelial cell barrier function. [PDF]
Karpurapu M +11 more
europepmc +1 more source
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Specialised lipid mediators and their targets
Seminars in Immunology, 2015Inflammation is a complex process governed by the interaction of multiple cell types of the innate immune system and secreted mediators. Such mediators may act in a paracrine or autocrine fashion on target effector cells. An appropriate inflammatory response is characterised by dynamically regulated initiation, propagation and eventual resolution and ...
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Lipid Mediators of Insulin Resistance
Nutrition Reviews, 2007Lipid abnormalities such as obesity, increased circulating free fatty acid levels, and excess intramyocellular lipid accumulation are frequently associated with insulin resistance. These observations have prompted investigators to speculate that the accumulation of lipids in tissues not suited for fat storage (e.g., skeletal muscle and liver) is an ...
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Lipid Mediators of Inflammation
Rheumatic Disease Clinics of North America, 1987Many mediators of inflammation are derived from phospholipids and polyunsaturated fatty acids, including prostaglandins, leukotrienes, and platelet-activating factor. These mediators augment the vascular phase of inflammation and modify functions of inflammatory cells and cells of the immune system.
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