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FABP4‐mediated lipid droplet accumulation drives epithelial–mesenchymal transition and aggravates alveolar epithelial barrier disruption

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Zihao Shen   +11 more
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Lipid Mediators of Inflammation

Rheumatic Disease Clinics of North America, 1987
Many mediators of inflammation are derived from phospholipids and polyunsaturated fatty acids, including prostaglandins, leukotrienes, and platelet-activating factor. These mediators augment the vascular phase of inflammation and modify functions of inflammatory cells and cells of the immune system.
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Lipid Mediators of Insulin Resistance

Nutrition Reviews, 2007
Lipid abnormalities such as obesity, increased circulating free fatty acid levels, and excess intramyocellular lipid accumulation are frequently associated with insulin resistance. These observations have prompted investigators to speculate that the accumulation of lipids in tissues not suited for fat storage (e.g., skeletal muscle and liver) is an ...
William L, Holland   +5 more
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Lipid mediators regulating pain sensitivity

Prostaglandins & Other Lipid Mediators, 2005
The papers in this symposium demonstrate that lipid molecules are ubiquitous messengers that participate in intracellular signaling, function in intercellular communication, and serve as neurotransmitters. This review examines the contribution of lipid messengers in regulating a specific physiological function, the transmission of noxious sensory ...
T Philip, Malan, Frank, Porreca
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Lipid hydroperoxide-mediated DNA damage

Experimental Gerontology, 2001
Lipid hydroperoxides are formed in vivo through free radical pathways from the action of reactive oxygen species on polyunsaturated fatty acids. They are also formed as specific products of lipoxygenases and cyclooxygenases. Homolytic decomposition of lipid hydroperoxides to the alpha,beta-unsaturated aldehyde genotoxins, 4-oxo-2-nonenal, 4,5-epoxy-2(E)
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[Lipid mediators].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1994
L, Kemeny, T, Ruzicka
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Rethinking lipid mediators

The Lancet, 2005
Karsten H, Weylandt, Jing X, Kang
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Ischemic Brain Damage: Focus On Lipids And Lipid Mediators

1992
The last two decades of research have produced detailed information not only on how ischemia causes degradation of phospholipids and accumulation of potentially cytotoxic breakdown products of such lipids, but also on reactions elicited by the subsequent conversion of these products into a series of lipids, mediating an array of cellular and ...
B K, Siesjö, K, Katsura
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