Results 261 to 270 of about 847,311 (317)

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Structural investigation of interactions between halogenated flavonoids and the lipid membrane along with their role as cytotoxic agents. [PDF]

open access: yesSci Rep
Dudek A   +7 more
europepmc   +1 more source
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Lipid-lipid and lipid-protein interactions in membranes

Pharmacology Biochemistry and Behavior, 1980
Over the past decade spectroscopic methods (fluorescence, ESR, and NMR) have been used to provide new information about the molecular dynamics of lipid-lipid and lipid-protein interactions in membranes. The various methods of characterizing isotropic and anisotropic motion are described.
P C, Jost, O H, Griffith
openaire   +2 more sources

Membranes and bioactive lipids

Biochimie, 2013
International ...
Girard-Egrot, Agnès, Lagarde, Michel
openaire   +4 more sources

Membrane Lipid Nanodomains

Chemical Reviews, 2018
Lipid membranes can spontaneously organize their components into domains of different sizes and properties. The organization of membrane lipids into nanodomains might potentially play a role in vital functions of cells and organisms. Model membranes represent attractive systems to study lipid nanodomains, which cannot be directly addressed in living ...
Marek Cebecauer   +6 more
openaire   +3 more sources

Lipids in amniotic membranes

American Journal of Obstetrics and Gynecology, 1965
Abstract 1. 1. Total lipids, phospholipids, esterified fatty acids (EFA), and cholesterol were studied in 167 amniotic membranes. These membranes were taken from 60 women of European origin, 63 women of Oriental origin, and 44 women of Yemenite origin. Venous blood was also studied for total lipids in these three groups of women. 2. 2.
W Z, POLISHUK, J, BOXER, R, GANZFRIED
openaire   +2 more sources

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