Results 51 to 60 of about 713,132 (303)

OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation [PDF]

, 2010
The dynamin-related GTPase OPA1 is mutated in autosomal dominant optic atrophy (DOA) (Kjer type), an inherited neuropathy of the retinal ganglion cells.
Alexander, Amati-Bonneau, Ardail, David C. Chan, Delettre, Delettre, Detmer, DeVay, Frezza, Griparic, Herlan, Heymann, Hudson, Ingerman, Jenny E. Hinshaw, Jürgen A.W. Heymann, Leonard, Meeusen, Olichon, Praefcke, Pucadyil, Rujiviphat, Sesaki, Song, Song, Tadato Ban, Tondera, Zhiyin Song, Zick   +28 more
core   +3 more sources

The influence of solid scaffolds on flat and curved lipid membranes

AIP Advances, 2017
Solid-supported membranes have become a common tool to study lipid membrane properties in a controlled environment. One particular example is the study of membrane curvature and its effect on lipid sorting.
D. H. de Jong, A. Heuer
doaj   +1 more source

Microparticle assembly pathways on lipid membranes [PDF]

, 2017
Understanding interactions between microparticles and lipid membranes is of increasing importance, especially for unraveling the influence of microplastics on our health and environment.
Heinrich, Doris, Kraft, Daniela J., van der Wel, Casper   +2 more
core   +3 more sources

Impact of Selected Small-Molecule Kinase Inhibitors on Lipid Membranes

Pharmaceuticals, 2021
Small-molecule protein kinase inhibitors are used for the treatment of various diseases. Although their effect(s) on the respective kinase are generally quite well understood, surprisingly, their interaction with membranes is only barely investigated ...
Meike Luck, Markus Fischer, Maximilian Werle, Holger A. Scheidt, Peter Müller   +4 more
doaj   +1 more source

Interplay Between Membrane Adhesion and Distribution of Lipid Rafts

Surfaces
Adhesion of cell membranes is relevant to many biological processes and arises from the specific binding of membrane-anchored receptor proteins to their ligands present in the apposing membrane.
Iyad Bin Hussain Thalakodan, Bartosz Różycki   +1 more
doaj   +1 more source

Lateral phase separation in mixtures of lipids and cholesterol [PDF]

, 2004
In an effort to understand "rafts" in biological membranes, we propose phenomenological models for saturated and unsaturated lipid mixtures, and lipid-cholesterol mixtures.
Bloom M., D Andelman, Dietrich C., Feigenson G. W., H Shirotori, Kessel A., Lawrence J. C., Lipowsky R., Lipowsky R., Nielsen M., P. D Olmsted, Pandit S. A., Priest R. G., S Komura, Sackmann E., Veatch S. L., Yuan C.   +16 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Lipid topogenesis

Journal of Lipid Research, 1981
Investigations of the topography of glycerolipid synthetic enzymes within the transverse plane of microsomal vesicles indicated an exclusive cytoplasmic surface location of active sites.
R M Bell, L M Ballas, R A Coleman
doaj   +1 more source

Geometry of membranes [PDF]

, 2011
This review reports some theoretical results on the Geometry of membranes. The governing equations to describe equilibrium configurations of lipid vesicles, lipid membranes with free edges, and chiral lipid membranes are derived from the variation of ...
Communicated Boris Konopeltchenko, Z. C. Tu   +1 more
core   +1 more source

Mitochondrial molecular chaperones [PDF]

, 1994
After synthesis in the cytosol, most mitochondrial proteins must traverse mitochondrial membranes to reach their functional location. During this process, proteins become unfolded and then refold to attain their native conformation after crossing the ...
Atencio, Caplan, Caplan, Cheng, Craig, Cyr, Deshales, Eilers, Gambill, Glick, Glick, Hartl, Hartl, Hwang, Johnson, Kang, Kiebler, Langer, Liberek, Manning-Krieg, Neupert, Ostermann, Palleros, Rassow, Rospert, Sanders, Scherer, Schleyer, Schröder, Simon, Vestweber, Voos, Xia   +32 more
core   +1 more source