Results 51 to 60 of about 3,712,736 (265)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Membranes, 2022 Lipid membranes are abundant in living organisms, where they constitute a surrounding shell for cells and their organelles. There are many circumstances in which the deformations of lipid membranes are involved in living cells: fusion and fission ...
Konstantin V. Pinigin
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Interactions of Novel Phosphonium Dye with Lipid Bilayers: A Molecular Dynamics Study
East European Journal of Physics, 2022 In the present work the 100-ns molecular dynamics simulations (MD) were performed in the CHARMM36m force field using the GROMACS package to estimate the bilayer location and mechanisms of the interaction between the novel phosphonium dye TDV and the ...
Olga Zhytniakivska
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Selective membrane wetting of phase-separated giant unilamellar vesicles by coacervate droplets
Nature CommunicationsLiquid-liquid phase separation (LLPS) has emerged as a key biological paradigm, playing a critical role in cellular compartmentalization and potentially contributing to the origins of life.
Emmanuel Joseph +3 more
doaj +1 more source
Non-Brownian diffusion in lipid membranes: Experiments and simulations.
Biochimica et Biophysica Acta, 2016 The dynamics of constituents and the surface response of cellular membranes-also in connection to the binding of various particles and macromolecules to the membrane-are still a matter of controversy in the membrane biophysics community, particularly ...
R. Metzler +2 more
semanticscholar +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Interaction of hydrophobic polymers with model lipid bilayers
Scientific Reports, 2017 The interaction of nanoscale synthetic materials with cell membranes is one of the key steps determining nanomaterials’ toxicity. Here we use molecular simulations, with atomistic and coarse-grained resolution, to investigate the interaction of three ...
D. Bochicchio +3 more
doaj +1 more source
The Effect of Tethers on Artificial Cell Membranes: A Coarse-Grained Molecular Dynamics Study. [PDF]
PLoS ONE, 2016 Tethered bilayer lipid membranes (tBLMs) provide a stable platform for modeling the dynamics and order of biological membranes where the tethers mimic the cytoskeletal supports present in biological cell membranes.
William Hoiles +4 more
doaj +1 more source