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Interplay Between Membrane Adhesion and Distribution of Lipid Rafts
SurfacesAdhesion of cell membranes is relevant to many biological processes and arises from the specific binding of membrane-anchored receptor proteins to their ligands present in the apposing membrane.
Iyad Bin Hussain Thalakodan +1 more
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Exploring the Impact of Lipid Domain Size on the Lifetime: A Dissipative Particle Dynamics Study
East European Journal of Physics, 2023 In this research, we have used the dissipative particle dynamics (DPD), a mesoscopic simulation technique, in order to investigate the dynamics of lipid domains in near critical temperature. Our specific focus has been on exploring the influence of lipid
Kan Sornbundit
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Lipids and Membrane Lateral Organization [PDF]
frontiers in physiology, 2010 Shortly after the elucidation of the very basic structure and properties of cellular membranes, it became evident that cellular membranes are highly organized structures with multiple and multi-dimensional levels of order. Very early observations suggested that the lipid components of biological membranes might be active players in the creation of ...
S. Sonnino, A.E.G. Prinetti
openaire +4 more sources
Breaking the membrane heredity paradox through de novo protocell formation
Nature CommunicationsLipid membranes define cell boundaries, acting as gatekeepers for transport and signaling. A central paradigm in biology is that all cellular membranes descend from a common ancestral membrane, as they cannot be generated in the absence of pre-existing ...
Satyam Khanal +4 more
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Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Manipulation of lipid rafts in neuronal cells [PDF]
, 2010 Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core
Journal of Lipid Research, 1981 Investigations of the topography of glycerolipid synthetic enzymes within the transverse plane of microsomal vesicles indicated an exclusive cytoplasmic surface location of active sites.
R M Bell, L M Ballas, R A Coleman
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Impact of Selected Small-Molecule Kinase Inhibitors on Lipid Membranes
Pharmaceuticals, 2021 Small-molecule protein kinase inhibitors are used for the treatment of various diseases. Although their effect(s) on the respective kinase are generally quite well understood, surprisingly, their interaction with membranes is only barely investigated ...
Meike Luck +4 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source