Results 71 to 80 of about 713,132 (303)

HIV-1 Gag Polyprotein Affinity to the Lipid Membrane Is Independent of Its Surface Charge

open access: yesBiomolecules
The binding of the HIV-1 Gag polyprotein to the plasma membrane is a critical step in viral replication. The association with membranes depends on the lipid composition, but its mechanisms remain unclear.
Zaret G. Denieva   +2 more
doaj   +1 more source

Transepidermal water loss: the signal for recovery of barrier structure and function.

open access: yesJournal of Lipid Research, 1989
Previous studies have demonstrated that perturbations in barrier function stimulate epidermal lipid synthesis and that this increase can be prevented by occlusive membranes.
G Grubauer, P M Elias, K R Feingold
doaj   +1 more source

Odor Discrimination by Lipid Membranes

open access: yesMembranes, 2023
Odor detection and discrimination in mammals is known to be initiated by membrane-bound G-protein-coupled receptors (GPCRs). The role that the lipid membrane may play in odor discrimination, however, is less well understood.
Troy W. Lowry   +3 more
doaj   +1 more source

Membrane Lipid Switches: How Membrane Lipid Structure Influences Protein–Lipid Interactions [PDF]

open access: yes, 2020
Peripheral membrane proteins are required for signal propagation upon ligand-induced receptor activation at the plasma membrane. The translocation of this amphitropic peripheral proteins from or to the plasma membrane enables signal cascade propagation into the cells.
Manuel Torres   +4 more
openaire   +1 more source

Molecular Structure Influences the Stability of Membrane Penetrating Biointerfaces. [PDF]

open access: yes, 2011
20.07.15 KB. Ok to add accepted version, 12 months embargo expired.Nanoscale patterning of hydrophobic bands on otherwise hydrophilic surfaces allows integration of inorganic structures through biological membranes, reminiscent of transmembrane proteins.
Almquist, BD, Melosh, NA
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Impact of monoolein on aquaporin1-based supported lipid bilayer membranes

open access: yesScience and Technology of Advanced Materials, 2015
Aquaporin (AQP) based biomimetic membranes have attracted considerable attention for their potential water purification applications. In this paper, AQP1 incorporated biomimetic membranes were prepared and characterized.
Zhining Wang   +5 more
doaj   +1 more source

Binding of the small-molecule kinase inhibitor ruxolitinib to membranes does not disturb membrane integrity

open access: yesBiochemistry and Biophysics Reports, 2020
Ruxolitinib is a small-molecule protein kinase inhibitor, which is used as a therapeutic agent against several diseases. Due to its anti-inflammatory impact, ruxolitinib has also been considered recently for usage in the treatment of Covid-19.
Markus Fischer   +4 more
doaj   +1 more source

Charge-induced phase separation in lipid membranes [PDF]

open access: yes, 2014
The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of ...
Andelman, David   +5 more
core   +2 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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