Results 101 to 110 of about 1,481,010 (254)

Effects of exercise on l-carnitine and lipid metabolism in African catfish (Clarias gariepinus) fed different dietary l-carnitine and lipid levels [PDF]

, 2009
African catfish (Clarias gariepinus) were fed four isonitrogenous diets (34 % crude protein), each containing one of two lipid (100 or 180 g/kg) and two l-carnitine (15 or 1000 mg/kg) levels. After 81 d of feeding, thirty-two fish (body weight 32 g) from
Ozorio, R.O.A., Verreth, J.A.J., Ginneken, V.J.T., van, Bessa, R.J.B., Verstegen, M.W.A., Huisman, E.A., Vincent J. T. Van Ginneken, Rui J. B. Bessa, Elbertus A. Huisman, Johan A. J. Verreth, Martin W. A. Verstegen, Rodrigo O. A. Ozorio   +11 more
core   +1 more source

Non-Targeted Serum Lipidomics Analysis and Potential Biomarkers of Laryngeal Cancer Based on UHPLC-QTOF-MS

, 2022
Laryngeal cancer is a common head and neck malignant cancer type. However, effective biomarkers for diagnosis are lacking and pathogenesis is unclear. Lipidomics is a powerful tool for identifying biomarkers and explaining disease mechanisms.
Min Ji, Hongwei Hou, Chen, Huan, Yanbo Luo, Huan Chen, Ji, Min, Wang, Haoyue, Hou, Hongwei, Hu, Qingyuan, Qingyuan Hu, Haoyue Wang, Luo, Yanbo   +11 more
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21 [PDF]

, 2009
OBJECTIVE—Fibroblast growth factor (FGF)-21 improves insulin sensitivity and lipid metabolism in obese or diabetic animal models, while human studies revealed increased FGF-21 levels in obesity and type 2 diabetes.
Pfeiffer, Andreas F. H., Meinus, S., Andres, Janin, Biedasek, Katrin, Biedasek, K., Spranger, J., Mai, K., Reinecke, F., Spuler, S., Pfeiffer, A.F., Moehlig, M., Sabath, Markus, Clemenz, M., Mai, Knut, Bobbert, T., Meinus, Sabine, Spranger, Joachim, Reinecke, Franziska, Weickert, Martin O., Bobbert, Thomas, Weicht, J., Möhlig, Matthias, Andres, J., Weicht, Jessica, Kintscher, U., Spuler, Simone, Clemenz, Markus, Sabath, M., Weickert, M.O., Kintscher, Ulrich   +29 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Lipids and lipid metabolism in the eye [PDF]

Journal of Lipid Research, 2009
The vertebrate eye is a complex sensory organ consisting of multiple, distinct tissues, each having its own unique biochemical composition, structure, and physiological function. Key among these are the retina, lens, and cornea, working in concert to bring photons of light into the eye, focus them correctly on the retina, and convert their energy into ...
openaire   +4 more sources

Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway

International Journal of Endocrinology, 2018
After activation, G protein-coupled receptors (GPCRs) are desensitized by β-arrestins (ARRBs). Moreover, ARRBs can initiate a second wave of signaling independent of G proteins. Thyroid-stimulating hormone receptor (TSHR) is one of the GPCR members.
Shaona Niu, Hui Li, Wenbin Chen, Jiajun Zhao, Ling Gao, Tao Bo   +5 more
doaj   +1 more source

Effects of gender and menopausal status on plasma lipoprotein subspecies and particle sizes

Journal of Lipid Research, 1996
The risk of coronary heart disease (CHD) is lower in women than in men, but increases in women after menopause. Some of the gender, age, and menopausal-related differences in CHD risk may relate to differences in lipoprotein subspecies.
Z Li, J R McNamara, J C Fruchart, G Luc, J M Bard, J M Ordovas, P W Wilson, E J Schaefer   +7 more
doaj   +1 more source

Lipid Metabolism and Statin Therapy in Neurodegenerative Diseases: An Endocrine View

Background/aim: A growing body of evidence suggests a link between dyslipidemias and neurodegenerative diseases, highlighting the crucial role of lipid metabolism in the health of the central nervous system.
Antonella Di Sarno, Silvia Savastano, Rossana Arianna, Annamaria Colao, Fiammetta Romano, Domenico Serpico, Carolina Di Somma, Mariarosaria Lavorgna   +7 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source