Results 61 to 70 of about 1,216,026 (349)

Bidirectional hybrid erythritol-inducible promoter for synthetic biology in Yarrowia lipolytica

Microbial Cell Factories, 2023
Background The oleaginous yeast Yarrowia lipolytica is increasingly used as a chassis strain for generating bioproducts. Several hybrid promoters with different strengths have been developed by combining multiple copies of an upstream activating sequence
Lea Vidal, Esteban Lebrun, Young-Kyoung Park, Guillaume Mottet, Jean-Marc Nicaud   +4 more
doaj   +1 more source

The Effects of Probiotics/Synbiotics on Glucose and Lipid Metabolism in Women with Gestational Diabetes Mellitus: A Meta-Analysis of Randomized Controlled Trials [PDF]

, 2023
Jinhao Mu, Xian Guo, Yanbing Zhou, Guoxia Cao   +3 more
openalex   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Hepatitis C virus relies on lipoproteins for its life cycle [PDF]

, 2016
Hepatitis C virus (HCV) infects over 150 million people worldwide. In most cases, HCV infection becomes chronic causing liver disease ranging from fibrosis to cirrhosis and hepatocellular carcinoma.
Alonzi, Tonino, DI CAPRIO, Giorgia, Fimia, Gian Maria, Grassi, Germana, Ippolito, Giuseppe, Tripodi, Marco   +5 more
core   +1 more source

Liver ACOX1 regulates levels of circulating lipids that promote metabolic health through adipose remodeling

Nature Communications
The liver gene expression of the peroxisomal β-oxidation enzyme acyl-coenzyme A oxidase 1 (ACOX1), which catabolizes very long chain fatty acids (VLCFA), increases in the context of obesity, but how this pathway impacts systemic energy metabolism remains
Dongliang Lu, Anyuan He, Min Tan, Marguerite Mrad, Amal El Daibani, Donghua Hu, Xuejing Liu, Brian Kleiboeker, Tao Che, Fong-Fu Hsu, Monika Bambouskova, Clay F. Semenkovich, Irfan J. Lodhi   +12 more
doaj   +1 more source

Current Therapeutical Approaches Targeting Lipid Metabolism in NAFLD [PDF]

, 2023
Manuela Vitulo, Elisa Gnodi, Giulia Rosini, Raffaella Meneveri, Roberto Giovannoni, Donatella Barisani   +5 more
openalex   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function [PDF]

, 2017
It is well established that cholesterol and glycosphingolipids are enriched in the plasma membrane (PM) and form signalling platforms called lipid rafts, essential for T-cell activation and function.
Adlanmerini, Aktas, al Yacoub, Araldi, Ashdown, Balamuth, Bensinger, Bovenga, Brown, Burridge, Chaudhri, Cho, Clark, Daniel, Degroote, Della Torre, Dimeloe, Dunn, Fievet, Foryst-Ludwig, Fox, Gaudet, Gervois, Greenwood, Griffié, Guo, Harris, Herold, Horton, Hughes, Ifergan, Iida, Ikonen, Ishikawa, Ito, Janes, Jeong, Jones, Jury, Jury, Jury, Kanakasabai, Keller, Kidani, Kidani, Kidani, Kirchgessner, Kishimoto, Klein, Kosters, Köberlin, Lappano, Lee, Levental, Levental, Levin, Lingwood, Lisse, Lovett-Racke, Lund, Luquet, Magee, McDonald, Megha, Mesmin, Miguel, Molnár, Nagafuku, Nazarov-Stoica, Ngo, Nuñez, Oliver, Owen, Owen, Pelekanou, Phiel, Quinet, Radhakrishnan, Repa, Rong, Rubin-Delanchy, Sankaran-Walters, Simigdala, Simons, Spann, Steffensen, Sun, Svenson, Swamy, Swinnen, Tang, Tcherepanova, Thangavel, Uppal, Uppal, Varga, Waddington, Waddington, Walcher, Wang, Wang, Wang, Wang, Wang, Wu, Yang, Youssef, Zalba, Zelcer, Zhu   +109 more
core   +2 more sources

Characterization of high density lipoprotein particles in familial apolipoprotein A-I deficiency1

Journal of Lipid Research, 2008
Our aim was to characterize HDL subspecies and fat-soluble vitamin levels in a kindred with familial apolipoprotein A-I (apoA-I) deficiency. Sequencing of the APOA1 gene revealed a nonsense mutation at codon −2, Q[−2]X, with two documented homozygotes ...
Raul D. Santos, Ernst J. Schaefer, Bela F. Asztalos, Eliana Polisecki, Jian Wang, Robert A. Hegele, Lilton R.C. Martinez, Marcio H. Miname, Carlos E. Rochitte, Protasio L. Da Luz, Raul C. Maranhão   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source