Results 61 to 70 of about 3,232,425 (402)

The ancient phosphatidylinositol 3-kinase signaling system is a master regulator of energy and carbon metabolism in algae [PDF]

open access: yes, 2018
Algae undergo a complete metabolic transformation under stress by arresting cell growth, inducing autophagy and hyperaccumulating biofuel precursors such as triacylglycerols and starch.
Byung-Hyuk Kim   +13 more
core   +2 more sources

A method for the rapid qualitative and quantitative analysis of 4,4-dimethyl sterols

open access: yesJournal of Lipid Research, 1973
A simple and relatively rapid technique has been developed for the separation of several 4,4-dimethyl steryl acetates, some of which contain sterically hindered nuclear double bonds.
G.F. Gibbons   +2 more
doaj   +1 more source

Concept of lipid droplet biogenesis

open access: yesEuropean Journal of Cell Biology, 2023
Lipid droplets (LD) are functionally conserved fat storage organelles found in all cell types. LDs have a unique structure comprising of a hydrophobic core of neutral lipids (fat), triacylglycerol (TAG) and cholesterol esters (CE) surrounded by a ...
R.Mankamna Kumari   +3 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome

open access: yesJournal of Lipid Research
Metabolic syndrome affects more than one in three adults and is associated with increased risk of diabetes, cardiovascular disease, and all-cause mortality.
Samantha E. Adamson   +12 more
doaj   +1 more source

Plasma apolipoprotein changes in the triglyceride-rich lipoprotein fraction of human subjects fed a fat-rich meal

open access: yesJournal of Lipid Research, 1988
Twenty two subjects (9 males, 13 females) were fed a fat-rich meal (1 g of fat/kg body weight). Triglyceride-rich lipoproteins (TRL) were isolated by ultracentrifugation (d less than 1.006 g/ml) from blood drawn 0, 3, 6, 9, and 12 hr after the meal ...
J S Cohn   +4 more
doaj   +1 more source

Lipid Metabolism in Oncology: Why It Matters, How to Research, and How to Treat

open access: yesCancers, 2021
Simple Summary Metabolic reprogramming is gaining attentions as a hallmark of cancers. However, lipid metabolism has been difficult to analyze due to technical problems.
Y. Matsushita, Hayato Nakagawa, K. Koike
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Microbiota and bile acid profiles in retinoic acid-primed mice that exhibit accelerated liver regeneration. [PDF]

open access: yes, 2015
Background & aimsAll-trans Retinoic acid (RA) regulates hepatic lipid and bile acid homeostasis. Similar to bile acid (BA), RA accelerates partial hepatectomy (PHx)-induced liver regeneration.
Hu, Ying   +2 more
core   +2 more sources

PexRAP Inhibits PRDM16-Mediated Thermogenic Gene Expression

open access: yesCell Reports, 2017
How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Irfan J. Lodhi   +8 more
doaj   +1 more source

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