Results 121 to 130 of about 1,061,660 (313)

Surface Symphony: Orchestrating DPPC/DOPC Monolayer Behavior

Microscopy Research and Technique, EarlyView.
Langmuir trough and atomic force microscopy reveals the physical nature of DPPC and DOPC mixed monolayers. ABSTRACT This study investigates the impact of environmental factors and lipid composition on the structural and morphological properties of DPPC/DOPC (1,2‐Dipalmitoyl‐sn‐glycero‐3‐phosphocholine/1,2‐dioleoyl‐sn‐glycero‐3‐phosphocholine ...
Wisnu Arfian A. Sudjarwo, Jose L. Toca‐Herrera   +1 more
wiley   +1 more source

Direct measurement of single soft lipid nano-tubes: nano-scale information extracted in non-invasive manner

, 2012
We investigated the dynamics of single soft nano-tubes of phospholipids to extract nano-scale information such as size of tube, which are several tens to hundreds of nano-meters thick.
Ichikawa, Masatoshi, Yamamoto, Akihisa
core   +1 more source

H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis [PDF]

, 2002
dEndocytosis is required for efficient mitogen-activated protein kinase (MAPK) activation by activated growth factor receptors. We examined if H-Ras and K-Ras proteins, which are distributed across different plasma membrane microdomains, have equal ...
Hancock, J. F., Roy, S., Wyse, B.
core   +2 more sources

The Dual Role of Exosomes in the Tumor Microenvironment: From Pro‐Tumorigenic Signaling to Immune Modulation

Med Research, EarlyView.
Tumor‐derived exosomes influence proliferation, invasion, angiogenesis, metabolic adaptation, and resistance to therapy. They also shape the immune landscape by modulating antigen presentation, suppressing cytotoxic lymphocyte activity, and promoting the expansion of immunosuppressive cell populations. Although frequently associated with immune evasion,
Jiale Li, Jun Peng, Jiachong Wang, Zigui Chen   +3 more
wiley   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, EarlyView.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source

Daptomycin-Resistant Enterococcus faecalis Diverts the Antibiotic Molecule from the Division Septum and Remodels Cell Membrane Phospholipids [PDF]

, 2013
Treatment of multidrug-resistant enterococci has become a challenging clinical problem in hospitals around the world due to the lack of reliable therapeutic options. Daptomycin (DAP), a cell membrane-targeting cationic antimicrobial lipopeptide, is the
Arias, Arias, Arias, Barák, Bayer, Bertsche, Bogdanov, Boucher, CLSI, Cotroneo, Davlieva, Dixit, Fishov, Ganz, Hachmann, Hachmann, Hall, Jones, Jordan, Kawai, Kicia, Kristich, Kullar, Lunde, Mileykovskaya, Mileykovskaya, Mileykovskaya, Mishra, Mishra, Mishra, Mukhopadhyay, Munita, Munita, Munoz-Price, Muraih, Muraih, Panesso, Pereira, Petit, Pogliano, Pogliano, Rosch, Sabol, Tsai, Vega, Yang, Zasloff   +46 more
core   +2 more sources

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP/PS1 transgenic mice

Frontiers in Physiology, 2012
Alterations in the lipid composition of lipid rafts have been demonstrated both in human brain and transgenic mouse models, and it has been postulated that aberrant lipid composition in lipid rafts is partly responsible for neuronal degeneration.
Mario L Diaz, Noemi eFabelo, Raquel eMarin   +2 more
doaj   +1 more source

Weak Glycolipid Binding of a Microdomain-Tracer Peptide Correlates with Aggregation and Slow Diffusion on Cell Membranes [PDF]

, 2012
10.1371/journal.pone.0051222PLoS ...
A Kakio, A Kakio, A Onufriev, Artur Matysik, B Hess, B Hess, B Windschiegl, BC Yowler, CA Lasagna-Reeves, CM Yip, CM Yip, CM Yip, D Lingwood, D Van der Spoel, D Zhang, DA Bateman, E Lindahl, G Bussi, GM Kuziemko, H Ewers, HJC Berendsen, J Fantini, J Fantini, J Fantini, J McLaurin, J McLaurin, J McLaurin, J Sankaran, JJ Kremer, JJ Kremer, JV Rocheleau, JV Rocheleau, K Bacia, K Bacia, K Ikeda, K Yanagisawa, K Yanagisawa, K Yanagisawa, K Yanagisawa, Kamila Oglęcka, L Johannes, L Saavedra, LP Choo-Smith, LP Choo-Smith, M Levy, M Stefl, M Wakabayashi, Manoj Manna, Maria Ruhnow, Michael Koval, MJ Widenbrant, MP Williamson, MR Baldwin, N Yamamoto, P Antes, P Critchley, R Pellizzari, R Roy, Rachel Kraut, RD Johnson, RH Swendsen, S Hebbar, S Inaba, S Manes, S Nag, S Steinert, SA Poulsen, SA Waschuk, Susana Geifman-Shochat, T Ariga, T Ariga, T Dertinger, T Valdes-Gonzalez, Thorsten Wohland, Tim Lauterbach, TS van Zanten, V Hornak, W Kabsch, W Romer, WI Weis, Yaofeng Wang, YC Lee, Yudi Wisantoso, Yuguang Mu, Z Petrasek   +84 more
core   +3 more sources

An Integrated Digital Microfluidic Device for the Extraction and Detection of Extracellular Vesicle‐Based Molecules

Small, EarlyView.
This work presents a proof‐of‐concept digital microfluidic device that can automatedly extract EVs from microliters of biological and physiological fluids within 25 min and detect EV‐bound protein markers on‐chip using electrochemical sensor. This work serves as a framework for the development of streamlined EV analysis in both medicine research and ...
Ting‐Wen Lo, Jing Liu, Yuqian Zhang, Yohan Kim, Janet Yao, Haidong Dong, Fabrice Lucien, Yuguang Liu   +7 more
wiley   +1 more source