Results 131 to 140 of about 1,147,179 (336)

Direct measurement of single soft lipid nano-tubes: nano-scale information extracted in non-invasive manner

open access: yes, 2012
We investigated the dynamics of single soft nano-tubes of phospholipids to extract nano-scale information such as size of tube, which are several tens to hundreds of nano-meters thick.
Ichikawa, Masatoshi, Yamamoto, Akihisa
core   +1 more source

H-Ras signaling and K-Ras signaling are differentially dependent on endocytosis [PDF]

open access: yes, 2002
dEndocytosis is required for efficient mitogen-activated protein kinase (MAPK) activation by activated growth factor receptors. We examined if H-Ras and K-Ras proteins, which are distributed across different plasma membrane microdomains, have equal ...
Hancock, J. F., Roy, S., Wyse, B.
core   +2 more sources

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim   +4 more
wiley   +1 more source

Sphingomyelin regulates the transcriptional machinery in nuclear lipid microdomains

open access: yesCommunications Biology
Nuclear lipid microdomains rich in sphingomyelin and cholesterol content regulate double-stranded exonuclease-resistant RNA. The study aimed to elucidate the importance of nuclear lipid microdomains in safeguarding nuclear RNA from digestion and to ...
Carmela Conte   +17 more
doaj   +1 more source

Lipid Segregation and Membrane Budding Induced by the Peripheral Membrane Binding Protein Annexin A2*

open access: yesJournal of Biological Chemistry, 2013
Background: Annexin A2 is a phospholipid binding protein implicated in endo- and exocytosis. Results: Annexin A2 induces microdomain formation and inward vesicle budding in giant unilamellar vesicles.
Patrick Drücker   +3 more
semanticscholar   +1 more source

ErbB receptorok szerepe epitél eredetű tumorokban: receptor tirozinkinázok, mint a tumor ellenes terápiák lehetséges target molekulái. = Role of ErbB receptors in epithelial tumors: receptor tyrosine kinases as targets for anticancer therapy. [PDF]

open access: yes, 2007
Az erbB2-erbB2 és erbB2-erbB1 molekulák homo- és heteroasszociációja - akárcsak más erbB hetero-oligomereké - fontos szerepet játszhatnak a jelátvitelben így az immunoterápiában is.
Barok, Márk   +8 more
core  

Structural diversity and biological significance of glycosphingolipids in pathogenic and opportunistic fungi [PDF]

open access: yes, 2014
Glycosphingolipids (GSLs) are ubiquitous membrane components and have key roles in biological systems, acting as second messengers or modulators of signal transduction by affecting several events, ranging from cell adhesion, cell growth, cell motility ...
Anita Hilda Straus   +5 more
core   +2 more sources

Valorization of Garcinia humilis Residues in Active Collagen/Starch Films for Biodegradable Packaging Applications

open access: yesPackaging Technology and Science, EarlyView.
Residues from Garcinia humilis were used to obtain a phenolic‐rich extract (GHRE) and incorporated into collagen–starch films. The addition of GHRE improved antioxidant activity, thermal stability and elasticity, while reducing water vapour permeability.
Érica da Costa Monção   +7 more
wiley   +1 more source

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