Results 151 to 160 of about 1,061,660 (313)

Overlooked aspects of CrRLK1L–RALF signaling

open access: yesNew Phytologist, EarlyView.
Summary Plant development relies on the ability of cells to coordinate growth with the cell wall's biomechanical status. Rapid alkalinization factors (RALFs) and their Catharanthus roseus RLK1‐like (CrRLK1L) kinase receptors form a dynamic signaling system linking wall sensing to growth regulation.
Sébastjen Schoenaers, Kris Vissenberg
wiley   +1 more source

Mapping the transcriptional landscape of algal resistance to viral infection reveals a core expression program

open access: yesNew Phytologist, EarlyView.
Summary Algal blooms and their demise by viruses drive global‐scale ecological processes in the ocean. These blooms form the foundation of marine food webs, regulate microbial communities, and shape biogeochemical cycles. Although algal populations are constantly infected by viruses, resistant subpopulations frequently emerge after the infection.
Talia S. Shaler   +5 more
wiley   +1 more source

A novel minimal in vitro system for analyzing HIV-1 Gag mediated budding

open access: yes, 2014
A biomimetic minimalist model membrane was used to study the mechanism and kinetics of cell-free in vitro HIV-1 Gag budding from a giant unilamellar vesicle (GUV).
Gill, Sarjeet   +7 more
core   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

Stearoyl-CoA Desaturase 1 Is a Key Determinant of Membrane Lipid Composition in 3T3-L1 Adipocytes.

open access: yesPLoS ONE, 2016
Stearoyl-CoA desaturase 1 (SCD1) is a lipogenic enzyme important for the regulation of membrane lipid homeostasis; dysregulation likely contributes to obesity associated metabolic disturbances. SCD1 catalyses the Δ9 desaturation of 12-19 carbon saturated
Sergio Rodriguez-Cuenca   +4 more
doaj   +1 more source

Direct evidence for microdomain-specific localization and remodeling of functional L-type calcium channels in rat and human atrial myocytes

open access: yes, 2015
Background—Distinct subpopulations of L-type calcium channels (LTCCs) with different functional properties exist in cardiomyocytes. Disruption of cellular structure may affect LTCC in a microdomain-specific manner and contribute to the pathophysiology of
Alvarez-Laviada, A   +13 more
core   +1 more source

Structure mirroring function: What's the ‘matter’ with the funny current?

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley   +1 more source

Safety and efficacy of docosahexaenoic acid supplementation during neoadjuvant breast cancer therapy: Findings from the phase II, double‐blind, randomized controlled DHA‐WIN trial

open access: yesInternational Journal of Cancer, Volume 157, Issue 7, Page 1405-1419, 1 October 2025.
What's New? Omega‐3 docosahexaenoic acid (DHA) has shown pleiotropic anti‐cancer effects both in vitro and in animal models. However, clinical evidence of DHA efficacy is limited. This randomized, double‐blind, placebo‐controlled trial tested the efficacy of supplementation with DHA 4.4 g/day during 18 weeks of breast cancer neoadjuvant chemotherapy ...
Jaqueline Munhoz   +16 more
wiley   +1 more source

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