Results 161 to 170 of about 1,061,660 (313)

Caveolae/lipid rafts in fibroblast-like synoviocytes: ectopeptidase-rich membrane microdomains [PDF]

open access: green, 2001
Dagmar Riemann   +8 more
openalex   +1 more source

Spatiotemporal Dynamics of Central Nervous System Diseases: Advancing Translational Neuropathology via Single‐Cell and Spatial Multiomics

open access: yesMedComm, Volume 6, Issue 9, September 2025.
Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia   +4 more
wiley   +1 more source

Structural insights into the membrane microdomain organization by SPFH family proteins

open access: yesCell Research, 2022
Chengying Ma   +6 more
semanticscholar   +1 more source

Exosomes in Metabolic Diseases: From Molecular Mechanisms to Clinical Applications

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
We summarize recent progress in exosome biology and elucidate their roles in interorgan communication networks underlying metabolic pathogenesis. We also comprehensively examine the evolving application of exosomes in metabolic disease management, with a focus on critically evaluating preclinical and clinical advances in exosome‐mediated therapeutic ...
Yanting Wu   +3 more
wiley   +1 more source

Analysis of Population Structure and Selection Signatures in Two Iraqi Fat‐Tailed Sheep Breeds

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Awassi sheep exhibit clear genetic separation, whereas Hamdani sheep show an admixed profile, with iHS, ROH and Tajima's D analyses identifying breed‐specific candidate genes. Enrichment in immune response, hormone regulation and cellular signalling pathways highlights adaptive evolution and guides future breeding and conservation.
Mervan Bayraktar   +6 more
wiley   +1 more source

Apo AI/ABCA1‐Dependent and HDL3‐Mediated Lipid Efflux from Compositionally Distinct Cholesterol‐Based Microdomains [PDF]

open access: bronze, 2002
Wolfgang Drobnik   +7 more
openalex   +1 more source

ATP8B1 Deficiency Causes Phosphodiesterase 4‐Mediated Glucagon Resistance and Impaired Gluconeogenesis in Mouse and Human Liver

open access: yesLiver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background and Aims Deficiency of the phospholipid transporter ATP8B1 causes infantile‐onset progressive familial intrahepatic cholestasis type I (PFIC1). Pre‐transplant PFIC1 patients often present with mild dyslipidaemia. This raises the possibility that PFIC1 patients, besides cholestasis, may also experience defects in glucose and lipid ...
Jung‐Chin Chang   +18 more
wiley   +1 more source

Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling [PDF]

open access: bronze, 2002
He Xiao   +4 more
openalex   +1 more source

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