Caveolae/lipid rafts in fibroblast-like synoviocytes: ectopeptidase-rich membrane microdomains [PDF]
Dagmar Riemann+8 more
openalex +1 more source
Central nervous system (CNS) diseases are driven by spatiotemporally dynamic molecular networks. Single‐cell and spatial multiomics technologies dissect cellular heterogeneity, microenvironmental remodeling, and intercellular crosstalk. Integration of transcriptomic, epigenomic, proteomic, and metabolomic layers reveals disease‐associated regulatory ...
Mingkai Xia+4 more
wiley +1 more source
Segregation of CD4 and CXCR4 into Distinct Lipid Microdomains in T Lymphocytes Suggests a Mechanism for Membrane Destabilization by Human Immunodeficiency Virus [PDF]
Susan L. Kozak+2 more
openalex +1 more source
Structural insights into the membrane microdomain organization by SPFH family proteins
Chengying Ma+6 more
semanticscholar +1 more source
Exosomes in Metabolic Diseases: From Molecular Mechanisms to Clinical Applications
We summarize recent progress in exosome biology and elucidate their roles in interorgan communication networks underlying metabolic pathogenesis. We also comprehensively examine the evolving application of exosomes in metabolic disease management, with a focus on critically evaluating preclinical and clinical advances in exosome‐mediated therapeutic ...
Yanting Wu+3 more
wiley +1 more source
Interaction of syncollin with GP-2, the major membrane protein of pancreatic zymogen granules, and association with lipid microdomains [PDF]
Ina Kalus+5 more
openalex +1 more source
Analysis of Population Structure and Selection Signatures in Two Iraqi Fat‐Tailed Sheep Breeds
Awassi sheep exhibit clear genetic separation, whereas Hamdani sheep show an admixed profile, with iHS, ROH and Tajima's D analyses identifying breed‐specific candidate genes. Enrichment in immune response, hormone regulation and cellular signalling pathways highlights adaptive evolution and guides future breeding and conservation.
Mervan Bayraktar+6 more
wiley +1 more source
Apo AI/ABCA1‐Dependent and HDL3‐Mediated Lipid Efflux from Compositionally Distinct Cholesterol‐Based Microdomains [PDF]
Wolfgang Drobnik+7 more
openalex +1 more source
ABSTRACT Background and Aims Deficiency of the phospholipid transporter ATP8B1 causes infantile‐onset progressive familial intrahepatic cholestasis type I (PFIC1). Pre‐transplant PFIC1 patients often present with mild dyslipidaemia. This raises the possibility that PFIC1 patients, besides cholestasis, may also experience defects in glucose and lipid ...
Jung‐Chin Chang+18 more
wiley +1 more source
Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling [PDF]
He Xiao+4 more
openalex +1 more source