Results 211 to 220 of about 1,147,179 (336)

Amyloid‐beta (1–40) peptide is associated with systemic metabolic health

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Plasma amyloid‐beta 1–40 (Aβ40) levels were measured in 449 individuals without overt cardiovascular disease. Higher Aβ40 was independently associated with metabolic syndrome, dyslipidemia (low HDL‐C, high triglycerides), insulin resistance (TyG index), diabetes mellitus and increased BARD score indicating liver fibrosis risk.
Kateryna Sopova   +12 more
wiley   +1 more source

Host membrane glycosphingolipids and lipid microdomains facilitateHistoplasma capsulatuminternalisation by macrophages

open access: gold, 2018
Allan J. Guimarães   +14 more
openalex   +2 more sources

Polar‐localized EXO70G1 regulates root development in Arabidopsis thaliana

open access: yesJournal of Integrative Plant Biology, Volume 68, Issue 1, Page 96-112, January 2026.
The putative exocyst subunit EXO70G1 exhibits apical‐basal polarity in Arabidopsis root cells; this polarity stabilizes membrane domains to facilitate targeting of the auxin transporter PIN‐FORMED2 during root development. ABSTRACT Cellular asymmetry, which represents a fundamental characteristic of cell polarity, is prominently illustrated by the ...
Juan Li   +11 more
wiley   +1 more source

Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cells [PDF]

open access: diamond, 2016
Chun‐Han Chen   +10 more
openalex   +1 more source

Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 20-43, January 2026.
Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli   +12 more
wiley   +1 more source

Piezo1 in intestinal smooth muscle cells: Emerging perspectives

open access: yesThe Journal of Physiology, Volume 604, Issue 1, Page 129-144, 1 January 2026.
Abstract figure legend Loss of Piezo1 in SMCs results in delayed gut transit, impaired small bowel contractility, and tissue alterations. But more critically, Piezo1 is shown to be intracellularly localized, highlighting important implications given the phenotype. Adapted from Bautista, G.M. et al.
Geoanna M. Bautista   +2 more
wiley   +1 more source

Disruption of Mitochondrial Dynamics and Integrity Drives Divergent Metabolic Flexibility and Resilience in Podocytes

open access: yesThe FASEB Journal, Volume 39, Issue 24, 31 December 2025.
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel   +13 more
wiley   +1 more source

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