Results 211 to 220 of about 1,147,179 (336)
Amyloid‐beta (1–40) peptide is associated with systemic metabolic health
Plasma amyloid‐beta 1–40 (Aβ40) levels were measured in 449 individuals without overt cardiovascular disease. Higher Aβ40 was independently associated with metabolic syndrome, dyslipidemia (low HDL‐C, high triglycerides), insulin resistance (TyG index), diabetes mellitus and increased BARD score indicating liver fibrosis risk.
Kateryna Sopova +12 more
wiley +1 more source
Polar‐localized EXO70G1 regulates root development in Arabidopsis thaliana
The putative exocyst subunit EXO70G1 exhibits apical‐basal polarity in Arabidopsis root cells; this polarity stabilizes membrane domains to facilitate targeting of the auxin transporter PIN‐FORMED2 during root development. ABSTRACT Cellular asymmetry, which represents a fundamental characteristic of cell polarity, is prominently illustrated by the ...
Juan Li +11 more
wiley +1 more source
Do lipid rafts exist? - Specialized microdomains and where to find them – a systematic review
Ivona Hlaj, Sara Bonet, Marija Heffer
openalex +2 more sources
Betulinic acid enhances TGF-β signaling by altering TGF-β receptors partitioning between lipid-raft/caveolae and non-caveolae membrane microdomains in mink lung epithelial cells [PDF]
Chun‐Han Chen +10 more
openalex +1 more source
Bioenergetics and lipid metabolism in Alzheimer's disease: From cell biology to systemic health
Abstract Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by progressive cognitive decline. Although amyloid‐β and tau pathologies remain central to our understanding of AD, growing evidence suggests that disrupted lipid metabolism and impaired bioenergetics are closely linked to these hallmark features. Genetic, lipidomic
Silvia Maioli +12 more
wiley +1 more source
Piezo1 in intestinal smooth muscle cells: Emerging perspectives
Abstract figure legend Loss of Piezo1 in SMCs results in delayed gut transit, impaired small bowel contractility, and tissue alterations. But more critically, Piezo1 is shown to be intracellularly localized, highlighting important implications given the phenotype. Adapted from Bautista, G.M. et al.
Geoanna M. Bautista +2 more
wiley +1 more source
We investigated two models of mitochondrial dysfunction in podocytes, using two cell culture models: podocytes isolated from mice with Oma1 deletion (Oma1del) and mouse podocytes modified with an inducible knockdown of PHB2 (Phb2kd). OMA1 deficiency induced a glycolytic shift, enhanced glutamine anaplerosis, and sustained energy homeostasis after ...
Cem Özel +13 more
wiley +1 more source

