Results 31 to 40 of about 1,147,179 (336)
Membranes, 2021 We characterized the size, distribution, and fluidity of microdomains in a lipid bilayer containing phosphatidylinositol (PI) and revealed their roles during the two-dimensional assembly of a membrane deformation protein (FBP17).
Toshinori Motegi +4 more
doaj +1 more source
The Journal of Experimental Medicine, 2002 Spatiotemporal aspects of filovirus entry and release are poorly understood. Lipid rafts act as functional platforms for multiple cellular signaling and trafficking processes. Here, we report the compartmentalization of Ebola and Marburg viral proteins within lipid rafts during viral assembly and budding.
Sina Bavari +9 more
openaire +1 more source
Lipid Microdomains in Cell Nucleus [PDF]
Molecular Biology of the Cell, 2008 It is known that nuclear lipids play a role in proliferation, differentiation, and apoptotic process. Cellular nuclei contain high levels of phosphatidylcholine and sphingomyelin, which are partially linked with cholesterol and proteins to form lipid–protein complexes.
Giacomo, Cascianelli +6 more
openaire +2 more sources
Function of Platelet Glycosphingolipid Microdomains/Lipid Rafts [PDF]
International Journal of Molecular Sciences, 2020 Lipid rafts are dynamic assemblies of glycosphingolipids, sphingomyelin, cholesterol, and specific proteins which are stabilized into platforms involved in the regulation of vital cellular processes. The rafts at the cell surface play important functions in signal transduction.
Keisuke Komatsuya +2 more
openaire +2 more sources
Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature. [PDF]
PLoS ONE, 2015 The formation of lipid microdomains ("rafts") is presumed to play an important role in various cellular functions, but their nature remains controversial.
Andrea Cremona +4 more
doaj +1 more source
Microdomain forming proteins in oncogenesis
Успехи молекулярной онкологии, 2016 Lipid rafts are lateral assembles of cholesterol, sphingomyelin, glicosphingolipids and specific proteins within cell plasma membrane. These microdomains are involved into a number of important cellular processes including membrane rearrangement, protein
I. B. Zborovskaya +2 more
doaj +1 more source
Anionic lipids enriched at the ExPortal of Streptococcus pyogenes [PDF]
, 2006 The ExPortal of Streptococcus pyogenes is a membrane microdomain dedicated to the secretion and folding of proteins. We investigated the lipid composition of the ExPortal by examining the distribution of anionic membrane phospholipids. Staining with 10-N-
Caparon, Michael G. +2 more
core +3 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundAtherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprotein ...
Sushma Kaul +13 more
doaj +1 more source
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1. [PDF]
FEBS LettTgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Nakatsuji T +5 more
europepmc +2 more sources
Journal of Lipid Research, 2005 The formation of hepatic bile requires that water be transported across liver epithelia. Rat hepatocytes express three aquaporins (AQPs): AQP8, AQP9, and AQP0. Recognizing that cholesterol and sphingolipids are thought to promote the assembly of proteins
P. Tietz +3 more
doaj +1 more source