Results 31 to 40 of about 1,061,660 (313)

The Regulatory Roles of Cerebellar Glycosphingolipid Microdomains/Lipid Rafts [PDF]

open access: goldInternational Journal of Molecular Sciences, 2023
Lipid rafts are dynamic assemblies of glycosphingolipids, sphingomyelin, cholesterol, and specific proteins which are stabilized into platforms involved in the regulation of vital cellular processes. Cerebellar lipid rafts are cell surface ganglioside microdomains for the attachment of GPI-anchored neural adhesion molecules and downstream signaling ...
Keisuke Komatsuya   +3 more
openalex   +3 more sources

Function of Platelet Glycosphingolipid Microdomains/Lipid Rafts [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Lipid rafts are dynamic assemblies of glycosphingolipids, sphingomyelin, cholesterol, and specific proteins which are stabilized into platforms involved in the regulation of vital cellular processes. The rafts at the cell surface play important functions in signal transduction.
Keisuke Komatsuya   +2 more
openaire   +2 more sources

Nuclear lipid microdomains regulate cell function [PDF]

open access: yesCommunicative & Integrative Biology, 2009
The lipids present in the nuclei play different roles in relation to their localization. They are composed by high levels of phosphatidylcholine and sphingomyelin strongly linked with cholesterol. The nuclear lipid composition shows many modifications during cell life due to the presence and activity of some specific enzymes such as sphingomyelinase ...
ALBI, Elisabetta, Villani, Maristella
openaire   +4 more sources

Microdomain forming proteins in oncogenesis

open access: yesУспехи молекулярной онкологии, 2016
Lipid rafts are lateral assembles of cholesterol, sphingomyelin, glicosphingolipids and specific proteins within cell plasma membrane. These microdomains are involved into a number of important cellular processes including membrane rearrangement, protein
I. B. Zborovskaya   +2 more
doaj   +1 more source

Roles for L o microdomains and ESCRT in ER stress-induced lipid droplet microautophagy in budding yeast

open access: yesMolecular Biology of the Cell, 2021
Microlipophagy (µLP), degradation of lipid droplets (LDs) by microautophagy, occurs by autophagosome-independent direct uptake of LDs at lysosomes/vacuoles in response to nutrient limitations and ER stressors in Saccharomyces cerevisiae.
Pin-Chao Liao   +4 more
semanticscholar   +1 more source

Anionic lipids enriched at the ExPortal of Streptococcus pyogenes [PDF]

open access: yes, 2006
The ExPortal of Streptococcus pyogenes is a membrane microdomain dedicated to the secretion and folding of proteins. We investigated the lipid composition of the ExPortal by examining the distribution of anionic membrane phospholipids. Staining with 10-N-
Caparon, Michael G.   +2 more
core   +3 more sources

Lipid‐Free Apolipoprotein A‐I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundAtherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprotein ...
Sushma Kaul   +13 more
doaj   +1 more source

Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion

open access: yesJournal of Lipid Research, 2005
The formation of hepatic bile requires that water be transported across liver epithelia. Rat hepatocytes express three aquaporins (AQPs): AQP8, AQP9, and AQP0. Recognizing that cholesterol and sphingolipids are thought to promote the assembly of proteins
P. Tietz   +3 more
doaj   +1 more source

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]

open access: yes, 2012
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ   +10 more
core   +1 more source

Lipid droplets in stress protection: distinct mechanisms of lipid droplet microautophagy

open access: yesAutophagy Reports, 2022
Lipid droplets (LDs) are organelles that function as sites for lipid storage. LDs have also been implicated in the cellular response to proteotoxic or lipotoxic stress as sites for sequestering dysfunctional or excess proteins or lipids, and targeting ...
Pin-Chao Liao, Liza A. Pon
doaj   +1 more source

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