Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ +10 more
core +1 more source
Membrane microdomains or rafts, sterol- and sphingolipid-rich microdomains in the plasma membrane have been studied extensively in mammalian cells. Recently, rafts were found to mediate virulence in a variety of parasites, including Toxoplasma gondii ...
Rikako Konishi +5 more
doaj +1 more source
Involvement of lipid microdomains in human endothelial cells infected by Streptococcus agalactiae type III belonging to the hypervirulent ST-17 [PDF]
BACKGROUND Streptococcus agalactiae capsular type III strains are a leading cause of invasive neonatal infections. Many pathogens have developed mechanisms to escape from host defense response using the host membrane microdomain machinery.
Beatriz Jandre Ferreira +5 more
doaj +2 more sources
Lipid droplets in stress protection: distinct mechanisms of lipid droplet microautophagy
Lipid droplets (LDs) are organelles that function as sites for lipid storage. LDs have also been implicated in the cellular response to proteotoxic or lipotoxic stress as sites for sequestering dysfunctional or excess proteins or lipids, and targeting ...
Pin-Chao Liao, Liza A. Pon
doaj +1 more source
Lipid rafts/caveolae as microdomains of calcium signaling [PDF]
Ca(2+) is a major signaling molecule in both excitable and non-excitable cells, where it serves critical functions ranging from cell growth to differentiation to cell death. The physiological functions of these cells are tightly regulated in response to changes in cytosolic Ca(2+) that is achieved by the activation of several plasma membrane (PM) Ca(2+)
Biswaranjan, Pani, Brij B, Singh
openaire +2 more sources
The membrane-associated form of α(s1)-casein interacts with cholesterol-rich detergent-resistant microdomains. [PDF]
Caseins, the main milk proteins, interact with colloidal calcium phosphate to form the casein micelle. The mesostructure of this supramolecular assembly markedly influences its nutritional and technological functionalities.
Annabelle Le Parc +5 more
doaj +1 more source
The polarization of sterol-enriched lipid microdomains has been linked to morphogenesis and cell movement in diverse cell types. Recent biochemical evidence has confirmed the presence of lipid microdomains in plant cells; however, direct evidence for a ...
P. Liu +7 more
semanticscholar +1 more source
Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir +7 more
core +1 more source
Segregation of lipids near acetylcholine-receptor channels imaged by cryo-EM
Rapid communication at the chemical synapse depends on the action of ion channels residing in the postsynaptic membrane. The channels open transiently upon the binding of a neurotransmitter released from the presynaptic nerve terminal, eliciting an ...
Nigel Unwin
doaj +1 more source
Lipids and membrane microdomains in HIV-1 replication [PDF]
Several critical steps in the replication cycle of human immunodeficiency virus type 1 (HIV-1) - entry, assembly and budding - are complex processes that take place at the plasma membrane of the host cell. A growing body of data indicates that these early and late steps in HIV-1 replication take place in specialized plasma membrane microdomains, and ...
Abdul A, Waheed, Eric O, Freed
openaire +2 more sources

