Results 51 to 60 of about 1,147,179 (336)

Fats and function:protein lipid modifications in plant cell signalling [PDF]

open access: yes, 2017
The post-translational lipid modifications N-myristoylation, prenylation and S-acylation are traditionally associated with increasing protein membrane affinity.
Adjobo-Hermans   +54 more
core   +2 more sources

C18:3-GM1a induces apoptosis in Neuro2a cells: enzymatic remodeling of fatty acyl chains of glycosphingolipids

open access: yesJournal of Lipid Research, 2005
GM1a [Galβ1-3GalNAcβ1-4(NeuAcα2-3)Galβ1-4Glcβ1-1Cer] is known to support and protect neuronal functions. However, we report that α-linolenic acid-containing GM1a (C18:3-GM1a), which was prepared using the reverse hydrolysis reaction of sphingolipid ...
Tetsuto Nakagawa   +5 more
doaj   +1 more source

The Effects of Cholesterol Oxidation on Erythrocyte Plasma Membranes: A Monolayer Study

open access: yesMembranes, 2022
Cholesterol plays a key role in the molecular and mesoscopic organisation of lipid membranes and it is expected that changes in its molecular structure (e.g., through environmental factors such as oxidative stress) may affect adversely membrane ...
Bob-Dan Lechner   +9 more
doaj   +1 more source

Metabotropic Purinergic Receptors in Lipid Membrane Microdomains

open access: yesCurrent Medicinal Chemistry, 2012
There is broad evidence that association of transmembrane receptors and signalling molecules with lipid rafts/caveolae provides an enriched environment for protein-protein interactions necessary for signal transduction, and a mechanism for the modulation of neurotransmitter and/or growth factor receptor function.
D' Ambrosi, N, Volonte, C
openaire   +4 more sources

Chitin perception in plasmodesmata characterizes submembrane immune-signaling specificity in plants [PDF]

open access: yes, 2020
The plasma membrane (PM) is composed of heterogeneous subdomains, characterized by differences in protein and lipid composition. PM receptors can be dynamically sorted into membrane domains to underpin signaling in response to extracellular stimuli.
Bellandi, Annalisa   +9 more
core   +2 more sources

Caveolae-Specific CaMKII Signaling in the Regulation of Voltage-Dependent Calcium Channel and Cardiac Hypertrophy

open access: yesFrontiers in Physiology, 2018
Cardiac hypertrophy is a major risk for the progression of heart failure; however, the underlying molecular mechanisms contributing to this process remain elusive.
Shota Tanaka   +2 more
doaj   +1 more source

Nuclear Lipid Microdomains Regulate Daunorubicin Resistance in Hepatoma Cells [PDF]

open access: yesInternational Journal of Molecular Sciences, 2018
Daunorubicin is an anticancer drug, and cholesterol is involved in cancer progression, but their relationship has not been defined. In this study, we developed a novel experimental model that utilizes daunorubicin, cholesterol, and daunorubicin plus cholesterol in the same cells (H35) to search for the role of nuclear lipid microdomains, rich in ...
Michela Codini   +12 more
openaire   +3 more sources

Exercise redox biochemistry:conceptual, methodological and technical recommendations [PDF]

open access: yes, 2017
Exercise redox biochemistry is of considerable interest owing to its translational value in health and disease. However, unaddressed conceptual, methodological and technical issues complicate attempts to unravel how exercise alters redox homeostasis in ...
Bailey, Damian M.   +3 more
core   +7 more sources

The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif

open access: yesBiology Open, 2013
Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains.
Peter G. Billcliff   +3 more
doaj   +1 more source

The Involvement of Lactosylceramide in Central Nervous System Inflammation Related to Neurodegenerative Disease

open access: yesFrontiers in Aging Neuroscience, 2021
Neurodegenerative diseases are a class of slow-progressing terminal illnesses characterized by neuronal lesions, such as multiple sclerosis [MS, Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS)]. Their incidence
Wen Yu   +16 more
doaj   +1 more source

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