Results 61 to 70 of about 1,147,179 (336)

Domain Growth Kinetics in a Cell-sized Liposome [PDF]

, 2005
We investigated the kinetics of domain growth on liposomes consisting of a ternary mixture (unsaturated phospholipid, saturated phospholipid, and cholesterol) by temperature jump.
Bagatolli L. A., Baumgart T., Brown D. A., Furukawa H., Hamada T., Imai M., Karatekin E., Komura S., Korlach J., Kusumi A., Laradji M., Lipowsky R., McConnell H. M., Momura S. M., Noireaux V., Ohki K., Roux A., Saffman P. G., Seul M., Silvius J. R., Simons K., Taniguchi T., Veatch S. L., Veatch S. L., Veatch S. L., Veatch S. L., Yamashita Y., Yu W.   +27 more
core   +3 more sources

Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function

Journal of Lipid Research, 2012
Fish oil (FO) targets lipid microdomain organization to suppress T-cell and macrophage function; however, little is known about this relationship with B cells, especially at the animal level. We previously established that a high FO dose diminished mouse
Benjamin Drew Rockett, Heather Teague, Mitchel Harris, Mark Melton, Justin Williams, Stephen R. Wassall, Saame Raza Shaikh   +6 more
doaj   +1 more source

An outlook on protein S-acylation in plants:what are the next steps? [PDF]

, 2017
S-acylation, also known as palmitoylation, is the reversible post-translational addition of fatty acids to proteins. Historically thought primarily to be a means for anchoring otherwise soluble proteins to membranes, evidence now suggests that reversible
Hemsley, Piers A.
core   +2 more sources

Lipidomic Comparison of Detergent-Soluble and Detergent-Resistant Lipid Domains Isolated From Rat Cerebellum and the Effect of Hypoxia-Ischemia Using UPLC-HDMS^E. [PDF]

J Mass Spectrom
ABSTRACT Hypoxic ischemic encephalopathy (HIE) due to insufficient oxygen or blood flow to the brain can result in inflammation, impaired neurodevelopment, or death. Changes to microdomain lipid composition may contribute to altered structure and function of key regulatory processes; however, knowledge regarding changes to membrane lipid composition ...
Krug SA, He M, Tang N, Bearer C, Kane MA.   +4 more
europepmc   +2 more sources

Variational Methods for Biomolecular Modeling

, 2016
Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs).
A Ivankin, A Jaramillo, A Warshel, AB Camley, B Lee, B Li, B Li, B Li, B Lu, B Lu, B Wang, BJ Reynwar, BR Brooks, C Mim, D Marsh, D Spoel Van Der, DG Thomas, DL Parton, E Gallicchio, E Gallicchio, EA Evans, F Campelo, FH Stillinger, FM Richards, FS Cohen, G Archontis, G-W Wei, G-W Wei, G-W Wei, GP Leser, GW Wei, HT McMahon, HY Lin, I Massova, I Park, IR Cooke, J Dzubiella, J Faraudo, J Gumbart, J Strain, J Wagoner, J Zimmerberg, JA Grant, JA Grant, JA Grant, JA Wagoner, JC Phillips, JC Stachowiak, JD Madura, JE Rothman, JMJ Swanson, K Farsad, K Lum, K Simons, KA Sharp, KM Callenberg, KS Kim, L-T Gao, LJ Pike, M Daily, M Feig, MD Huang, ME Davis, N Choudhury, N Gavish, NA Baker, NW Schmidt, O Sten-Knudsen, P Concus, P Grochowski, PB Canham, PW Bates, PW Bates, Q Du, Q Du, Q Du, Q Zheng, Q Zheng, R Brewster, R Brewster, R Parthasarathy, RA Pierotti, RE Skyner, RJ Ryham, S Choe, S Dai, S Li, S Osher, S Xu, S Zhao, S Zhao, SC Brenner, T Baumgart, T Kirchhausen, T Simonson, T Sollner, T Takahashi, T Witkowski, T-L Horng, V Luzhkov, VB Chu, W Geng, X Chen, X Chen, Y Tang, Y Wang, Y Wang, Y Wang, Y Zhao, YC Zhou, YC Zhou, Z Chen, Z Chen, Z Chen, ZY Yu   +114 more
core   +1 more source

The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs [PDF]

, 2016
The disruption of ionic and H-bond interactions between the cytosolic ends of transmembrane helices TM3 and TM6 of class-A (rhodopsin-like) G protein-coupled receptors (GPCRs) is a hallmark for their activation by chemical or physical stimuli.
Abusharkh, Alexov, Angelica Sandoval, Arnis, Ballesteros, Borisovska, Castile, Choe, Cohen, Dickson, Dizhoor, Dror, Fahmy, Fahmy, Farrens, Georgescu, Gleason, Herrmann, Hess, Hofmann, Hoover, Hornak, Jorgensen, Jäger, Jämbeck, Karim Fahmy, Khesbak, Kim, Knierim, Krishnakumar, Lagerström, Lew, Lüdeke, Madathil, Mahalingam, Maier, Miyamoto, Nosé, Nygaard, Opefi, Palczewski, Palczewski, Park, Parrinello, Philip J. Reeves, Pronk, Rainer A. Böckmann, Rockland, Scheerer, Shahidullah, Sheikh, Shi, Sineej Madathil, Song, Standfuss, Standfuss, Stefanie Eichler, Vivian, Vogel, Vogel, Wolf, Yan   +61 more
core   +1 more source

A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb3), eliminates the cholesterol requirement for high affinity gp120/Gb3 interaction

Journal of Lipid Research, 2002
We have analyzed the interaction of adamantyl Gb3 (adaGb3), a semi-synthetic soluble analog of Gb3, with HIV-1 surface envelope glycoprotein gp120. In this analog, which was orginally designed to inhibit verotoxin binding to its glycolipid receptor, Gb3,
Radhia Mahfoud, Murugesapillai Mylvaganam, Clifford A. Lingwood, Jacques Fantini   +3 more
doaj   +1 more source

The Regulatory Roles of Cerebellar Glycosphingolipid Microdomains/Lipid Rafts

International Journal of Molecular Sciences, 2023
Lipid rafts are dynamic assemblies of glycosphingolipids, sphingomyelin, cholesterol, and specific proteins which are stabilized into platforms involved in the regulation of vital cellular processes. Cerebellar lipid rafts are cell surface ganglioside microdomains for the attachment of GPI-anchored neural adhesion molecules and downstream signaling ...
Keisuke Komatsuya, Norihito Kikuchi, Tetsuya Hirabayashi, Kohji Kasahara   +3 more
openaire   +2 more sources

The trafficking and targeting of P2X receptors [PDF]

, 2013
The functional expression of P2X receptors at the plasma membrane is dependent on their trafficking along secretory and endocytic pathways. There are seven P2X receptor subunits, and these differ in their subcellular distributions because they have very ...
Murrell-Lagnado, Ruth D, Robinson, Lucy E   +1 more
core   +3 more sources

Thematic Review Series: Sphingolipids. Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review*1

Journal of Lipid Research, 2008
Gangliosides are expressed in the outer leaflet of the plasma membrane of the cells of all vertebrates and are particularly abundant in the nervous system. Ganglioside metabolism is closely associated with the pathology of Alzheimer's disease (AD).
Toshio Ariga, Michael P. McDonald, Robert K. Yu   +2 more
doaj   +1 more source